Article: Optimizing microencapsulation of α-tocopherol with pectin and sodium alginate

-Tocopherol is a well-known fat-soluble antioxidant and is widely used in the food industry for stabilizing free radicals. Incorporation and stability of it into food is another challenge as directly added -tocopherol is prone to inactivation by food constituents. This study was aimed at optimizing conditions for encapsulation of -tocopherol using combination of sodium alginate (0.5, 1.0, 1.5 and 2.0%) as primary wall material and pectin (2.0%) as filler. The optimum conditions were selected on the basis of encapsulation efficiency, shape, size, bulk density, yield and swelling index with syringe method. The encapsulation efficiency of -tocopherol in microencapsules produced under optimal conditions was 52.91% using sodium alginate 1.5% w/v and pectin 2.0% w/v. -Tocopherol was encapsulated with encapsulator using standard conditions and was compared with syringe method. The encapsulation efficiency was found more (55.97%) in microencapsules prepared with encapsulator and 52.11% in microencapsules prepared with syringe.

Citing Articles

Development of a microencapsulated probiotic delivery system with whey, xanthan, and pectin.

Bordini F, Rosolen M, da Luz G, Pohndorf R, de Oliveira P, Conceicao F Braz J Microbiol. 2023; 54(3):2183-2195.

PMID: 37434082 PMC: 10484871. DOI: 10.1007/s42770-023-01041-y.

Alginate Encapsulation Stabilizes Xylanase Toward the Laccase Mediator System.

Lee A, Gervasio E, Hughes R, Maalouf A, Musso S, Crisalli A Appl Biochem Biotechnol. 2022; 195(5):3311-3326.

PMID: 36585551 DOI: 10.1007/s12010-022-04296-7.

Preparation and Characteristics of Alginate Microparticles for Food, Pharmaceutical and Cosmetic Applications.

Letocha A, Miastkowska M, Sikora E Polymers (Basel). 2022; 14(18).

PMID: 36145992 PMC: 9502979. DOI: 10.3390/polym14183834.

Current Advancements in Pectin: Extraction, Properties and Multifunctional Applications.

Chandel V, Biswas D, Roy S, Vaidya D, Verma A, Gupta A Foods. 2022; 11(17).

PMID: 36076865 PMC: 9455162. DOI: 10.3390/foods11172683.

Alginate: From Food Industry to Biomedical Applications and Management of Metabolic Disorders.

Gheorghita Puscaselu R, Lobiuc A, Dimian M, Covasa M Polymers (Basel). 2020; 12(10).

PMID: 33092194 PMC: 7589871. DOI: 10.3390/polym12102417.

References

1.

Yoo S, Song Y, Chang P, Lee H . Microencapsulation of alpha-tocopherol using sodium alginate and its controlled release properties. Int J Biol Macromol. 2006; 38(1):25-30. DOI: 10.1016/j.ijbiomac.2005.12.013. View

2.

Wong T, Colombo G, Sonvico F . Pectin matrix as oral drug delivery vehicle for colon cancer treatment. AAPS PharmSciTech. 2011; 12(1):201-14. PMC: 3066368. DOI: 10.1208/s12249-010-9564-z. View

3.

Fu S, Thacker A, Sperger D, Boni R, Buckner I, Velankar S . Relevance of rheological properties of sodium alginate in solution to calcium alginate gel properties. AAPS PharmSciTech. 2011; 12(2):453-60. PMC: 3134659. DOI: 10.1208/s12249-011-9587-0. View

4.

Tsai W, Rizvi S . Simultaneous microencapsulation of hydrophilic and lipophilic bioactives in liposomes produced by an ecofriendly supercritical fluid process. Food Res Int. 2017; 99(Pt 1):256-262. DOI: 10.1016/j.foodres.2017.05.029. View

5.

Narsaiah K, Jha S, Bhardwaj R, Sharma R, Kumar R . Optical biosensors for food quality and safety assurance-a review. J Food Sci Technol. 2013; 49(4):383-406. PMC: 3550887. DOI: 10.1007/s13197-011-0437-6. View

Optimizing Microencapsulation of α-tocopherol with Pectin and Sodium Alginate