Human Proto-oncogene C-mos Maps to 8q11

Overview

Journal EMBO J

Specialties Biotechnology
Molecular Biology

Date 1985 Sep 1

PMID 3000766

Citations 22

Authors

J F Caubet

A Bernheim

C J Larsen

R Berger

Affiliations

Soon will be listed here.

Abstract

The c-mos proto-oncogene is the cellular counterpart of the viral oncogene v-mos isolated from Moloney murine sarcoma virus. The c-mos gene locus has previously been assigned to human chromosome 8. By both in situ hybridization and molecular hydridization to sorted chromosome DNA (using a c-mos probe) we have localized the c-mos gene to band 8q11. This regional localization is at variance with the one previously reported at 8q22 and may explain why no rearrangement of c-mos has been found in acute leukaemia with the chromosomal translocation t(8;21)(q22;q22).

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