Chromosome Assignment of Four RAS-related RAB Genes

Overview

Journal Hum Genet

Specialty Genetics

Date 1991 Feb 1

PMID 1999336

Citations 3

Authors

M F Rousseau-Merck

A Zahraoui

N Touchot

A Tavitian

R Berger

Affiliations

Soon will be listed here.

Abstract

The human RAB genes share structural and biochemical properties with the RAS gene superfamily. The encoded RAB proteins show 38 to 75% amino acid identity with the yeast YPT1 and SEC4 gene products. We used four human RAB-cDNAs, RAB3B, RAB4, RAB5 and RAB6, to map the corresponding genes on human chromosomes. These genes were assigned to 1p32-p31, 1q42-q43, 3p24-p22 and 2q14-q21, respectively, by in situ hybridization.

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