» Articles » PMID: 29106570

The UCSC Genome Browser Database: 2018 Update

Abstract

The UCSC Genome Browser (https://genome.ucsc.edu) provides a web interface for exploring annotated genome assemblies. The assemblies and annotation tracks are updated on an ongoing basis-12 assemblies and more than 28 tracks were added in the past year. Two recent additions are a display of CRISPR/Cas9 guide sequences and an interactive navigator for gene interactions. Other upgrades from the past year include a command-line version of the Variant Annotation Integrator, support for Human Genome Variation Society variant nomenclature input and output, and a revised highlighting tool that now supports multiple simultaneous regions and colors.

Citing Articles

LncRNA Recognition-Associated CpG Island Detection and Methylation Analysis.

You Y, Xiao M, Zhang L Methods Mol Biol. 2024; 2883:281-297.

PMID: 39702713 DOI: 10.1007/978-1-0716-4290-0_12.


The PNUTS phosphatase complex controls transcription pause release.

Kelley J, Dimitrova E, Maciuszek M, Nguyen H, Szczurek A, Hughes A Mol Cell. 2024; 84(24):4843-4861.e8.

PMID: 39603239 PMC: 11663112. DOI: 10.1016/j.molcel.2024.10.045.


Serial single-cell RNA sequencing unveils drug resistance and metastatic traits in stage IV breast cancer.

Otsuji K, Takahashi Y, Osako T, Kobayashi T, Takano T, Saeki S NPJ Precis Oncol. 2024; 8(1):222.

PMID: 39363009 PMC: 11450160. DOI: 10.1038/s41698-024-00723-6.


DRED: A Comprehensive Database of Genes Related to Repeat Expansion Diseases.

Shi Q, Dai M, Ma Y, Liu J, Liu X, Wang X Genomics Proteomics Bioinformatics. 2024; 22(5).

PMID: 39348154 PMC: 11696699. DOI: 10.1093/gpbjnl/qzae068.


A liver immune rheostat regulates CD8 T cell immunity in chronic HBV infection.

Bosch M, Kallin N, Donakonda S, Zhang J, Wintersteller H, Hegenbarth S Nature. 2024; 631(8022):867-875.

PMID: 38987588 PMC: 11269190. DOI: 10.1038/s41586-024-07630-7.


References
1.
Haeussler M, Raney B, Hinrichs A, Clawson H, Zweig A, Karolchik D . Navigating protected genomics data with UCSC Genome Browser in a Box. Bioinformatics. 2014; 31(5):764-6. PMC: 4341066. DOI: 10.1093/bioinformatics/btu712. View

2.
Blohm P, Frishman G, Smialowski P, Goebels F, Wachinger B, Ruepp A . Negatome 2.0: a database of non-interacting proteins derived by literature mining, manual annotation and protein structure analysis. Nucleic Acids Res. 2013; 42(Database issue):D396-400. PMC: 3965096. DOI: 10.1093/nar/gkt1079. View

3.
Schaefer C, Anthony K, Krupa S, Buchoff J, Day M, Hannay T . PID: the Pathway Interaction Database. Nucleic Acids Res. 2008; 37(Database issue):D674-9. PMC: 2686461. DOI: 10.1093/nar/gkn653. View

4.
Down T, Piipari M, Hubbard T . Dalliance: interactive genome viewing on the web. Bioinformatics. 2011; 27(6):889-90. PMC: 3051325. DOI: 10.1093/bioinformatics/btr020. View

5.
Bader G, Betel D, Hogue C . BIND: the Biomolecular Interaction Network Database. Nucleic Acids Res. 2003; 31(1):248-50. PMC: 165503. DOI: 10.1093/nar/gkg056. View