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Direct β-Selective Hydrocarboxylation of Styrenes with CO Enabled by Continuous Flow Photoredox Catalysis

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Journal J Am Chem Soc
Specialty Chemistry
Date 2017 Sep 28
PMID 28953365
Citations 33
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Abstract

The direct β-selective hydrocarboxylation of styrenes under atmospheric pressure of CO has been developed using photoredox catalysis in continuous flow. The scope of this methodology was demonstrated with a range of functionalized terminal styrenes, as well as α-substituted and β-substituted styrenes.

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