Aofei Liu
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Explore the profile of Aofei Liu including associated specialties, affiliations and a list of published articles.
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12
Citations
84
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Recent Articles
1.
Ng C, Liu A, Cui B, Banik S
Nature
. 2024 Sep;
633(8031):941-951.
PMID: 39294374
Subcellular protein localization regulates protein function and can be corrupted in cancers and neurodegenerative diseases. The rewiring of localization to address disease-driving phenotypes would be an attractive targeted therapeutic approach....
2.
Liu A, Mohr M, Hope J, Wang J, Chen X, Cui B
ACS Chem Biol
. 2024 Jul;
19(7):1626-1637.
PMID: 39026469
Chronic pain is a prevalent problem that plagues modern society, and better understanding its mechanisms is critical for developing effective therapeutics. Nerve growth factor (NGF) and its primary receptor, Tropomyosin...
3.
Saxena S, Foresti O, Liu A, Androulaki S, Pena Rodriguez M, Raote I, et al.
Dev Cell
. 2024 Jul;
59(19):2593-2608.e6.
PMID: 38991587
TANGO1, TANGO1-Short, and cTAGE5 form stable complexes at the endoplasmic reticulum exit sites (ERES) to preferably export bulky cargoes. Their C-terminal proline-rich domain (PRD) binds Sec23A and affects COPII assembly....
4.
Zhu C, Wang D, Chang C, Liu A, Zhou J, Yang T, et al.
Korean J Physiol Pharmacol
. 2024 Apr;
28(3):239-252.
PMID: 38682172
Dexmedetomidine displays multiple mechanisms of neuroprotection in ameliorating ischemic brain injury. In this study, we explored the beneficial effects of dexmedetomidine on blood-brain barrier (BBB) integrity and neuroinflammation in cerebral...
5.
Yang Y, Liu A, Tsai C, Liu C, Wu J, Cui B
Biosens Bioelectron
. 2022 Aug;
216:114617.
PMID: 36027802
Unintended binding of small-molecule drugs to ion channels affects electrophysiological properties of cardiomyocytes and potentially leads to arrhythmia and heart failure. The waveforms of intracellular action potentials reflect the coordinated...
6.
Jahed Z, Yang Y, Tsai C, Foster E, McGuire A, Yang H, et al.
Nat Commun
. 2022 Apr;
13(1):2253.
PMID: 35474069
Drug-induced cardiotoxicity arises primarily when a compound alters the electrophysiological properties of cardiomyocytes. Features of intracellular action potentials (iAPs) are powerful biomarkers that predict proarrhythmic risks. In the last decade,...
7.
Huang P, Liu A, Song Y, Hope J, Cui B, Duan L
J Mol Biol
. 2020 May;
432(13):3761-3770.
PMID: 32422149
Brain-derived neurotrophic factor, via activation of tropomyosin receptor kinase B (TrkB), plays a critical role in neuronal proliferation, differentiation, survival, and death. Dysregulation of TrkB signaling is implicated in neurodegenerative...
8.
Hope J, Liu A, Calvin G, Cui B
J Mol Biol
. 2020 Apr;
432(13):3739-3748.
PMID: 32335036
Receptor tyrosine kinases (RTKs) play crucial roles in human health, and their misregulation is implicated in disorders ranging from neurodegenerative diseases to cancers. The highly conserved mechanism of activation of...
9.
Jones 4th T, Liu A, Cui B
ACS Synth Biol
. 2020 Mar;
9(4):893-901.
PMID: 32212723
Nanoscale membrane curvature is now understood to play an active role in essential cellular processes such as endocytosis, exocytosis, and actin dynamics. Previous studies have shown that membrane curvature can...
10.
Liu A, Zhang J, Xing H, Yang Y
Appl Opt
. 2019 Sep;
58(19):5339-5346.
PMID: 31503634
Based on results from the Silvaco Atlas device simulation software, a separate absorption grading charge multiplication InGaAs/InP avalanche photodiode has been modeled. The Shockley-Read-Hall current, avalanche amplification current, trap-assisted tunneling...