Viral Persistence, Liver Disease, and Host Response in a Hepatitis C-like Virus Rat Model

Overview

Journal Hepatology

Specialty Gastroenterology

Date 2017 Sep 1

PMID 28859226

Citations 45

Authors

Sheetal Trivedi

Satyapramod Murthy

Himanshu Sharma

Alex S Hartlage

Arvind Kumar

Sashi V Gadi

Peter Simmonds

Lokendra V Chauhan

Troels K H Scheel

Eva Billerbeck

Peter D Burbelo

Charles M Rice

W Ian Lipkin

Kurt Vandegrift

John M Cullen

Amit Kapoor

Affiliations

Soon will be listed here.

Abstract

Conclusion: We developed RHV-rn1-infected rats as a fully immunocompetent and informative surrogate model to delineate the mechanisms of HCV-related viral persistence, immunity, and pathogenesis. (Hepatology 2018).

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