Eva Billerbeck
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Explore the profile of Eva Billerbeck including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
1604
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Recent Articles
1.
Lopez-Scarim J, Mendoza D, Nambiar S, Billerbeck E
PLoS Pathog
. 2024 Oct;
20(10):e1012615.
PMID: 39392861
In hepatitis C virus (HCV) infection, CD4+ and CD8+ T cells are crucial for viral control. However, a detailed understanding of the kinetic of CD4+ T cell help and its...
2.
Brown A, Won J, Wolfisberg R, Fahnoe U, Catanzaro N, West A, et al.
Hepatology
. 2023 Aug;
79(1):183-197.
PMID: 37540195
Background Aims: Human genetic variation is thought to guide the outcome of HCV infection, but model systems within which to dissect these host genetic mechanisms are limited. Norway rat hepacivirus,...
3.
Lopez-Scarim J, Nambiar S, Billerbeck E
Vaccines (Basel)
. 2023 Mar;
11(3).
PMID: 36992265
T cells play an important role in the clearance of hepatotropic viruses but may also cause liver injury and contribute to disease progression in chronic hepatitis B and C virus...
4.
Wolfisberg R, Holmbeck K, Billerbeck E, Thorselius C, Batista M, Fahnoe U, et al.
J Virol
. 2023 Mar;
97(4):e0181222.
PMID: 36971565
The lack of robust immunocompetent animal models for hepatitis C virus (HCV) impedes vaccine development and studies of immune responses. Norway rat hepacivirus (NrHV) infection in rats shares HCV-defining characteristics,...
5.
Raus S, Lopez-Scarim J, Luthy J, Billerbeck E
Front Immunol
. 2022 Sep;
13:953151.
PMID: 36159876
Chronic hepatitis C virus (HCV) infection is a curable disease, but the absence of a vaccine remains a major problem in infection prevention. The lack of small animal models and...
6.
Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al.
Cell
. 2017 Dec;
172(3):423-438.e25.
PMID: 29249360
Stem cells are highly resistant to viral infection compared to their differentiated progeny; however, the mechanism is mysterious. Here, we analyzed gene expression in mammalian stem cells and cells at...
7.
Trivedi S, Murthy S, Sharma H, Hartlage A, Kumar A, Gadi S, et al.
Hepatology
. 2017 Sep;
68(2):435-448.
PMID: 28859226
Conclusion: We developed RHV-rn1-infected rats as a fully immunocompetent and informative surrogate model to delineate the mechanisms of HCV-related viral persistence, immunity, and pathogenesis. (Hepatology 2018).
8.
Billerbeck E, Wolfisberg R, Fahnoe U, Xiao J, Quirk C, Luna J, et al.
Science
. 2017 Jul;
357(6347):204-208.
PMID: 28706073
An estimated 71 million people worldwide are infected with hepatitis C virus (HCV). The lack of small-animal models has impeded studies of antiviral immune mechanisms. Here we show that an...
9.
Billerbeck E, Mommersteeg M, Shlomai A, Xiao J, Andrus L, Bhatta A, et al.
J Hepatol
. 2016 May;
65(2):334-43.
PMID: 27151182
Background & Aims: Human liver chimeric mice are useful models of human hepatitis virus infection, including hepatitis B and C virus infections. Independently, immunodeficient mice reconstituted with CD34(+) hematopoietic stem...
10.
Billerbeck E, Labitt R, Vega K, Frias-Staheli N, Dorner M, Xiao J, et al.
Immunology
. 2014 Apr;
143(2):202-18.
PMID: 24766459
Differentiation of CD4(+) T cells into type 1 or type 2 subsets is mediated by the expression of the opposing lineage defining transcription factors T-bet and GATA-3. However, the existence...