Adherence to the Mediterranean Diet and All-Cause Mortality Risk in an Elderly Italian Population: Data from the ILSA Study
Overview
Nutritional Sciences
Authors
Affiliations
Objective: The aim of this study was to evaluate adherence to the Mediterranean Diet (MD) and its association with all-cause mortality in an elderly Italian population.
Design: Data analysis of a longitudinal study of a representative, age stratified, population sample.
Setting: Study data is based upon the Italian Longitudinal Study on Aging (ILSA) a prospective, community-based cohort study. The baseline evaluation was carried out in 1992 and the follow-up in 1996 and 2000.
Participant: Participant food intake assessment was available at baseline for 4,232 subjects; information on survival was available for 2,665 at the 2000 follow-up.
Measurements: Adherence to the MD was evaluated with an a priori score based on the Mediterranean pyramid components. Cox proportional hazard models were used to assess the relationship between the MD score and all-cause mortality. Six hundred and sixty five subjects had died at the second follow-up (identified up to the first and second follow-up together; mean follow-up: 7.1±2.6 years).
Results: At the 2000 follow-up, adjusting for other confounding factors, participants with a high adherence to MD (highest tertile of the MD score distribution) had an all-cause mortality risk that was of 34% lower with respect to the subjects with low adherence (Hazard Ratio=0.66; 95% CI: 0.49-0.90; p=0.0144).
Conclusion: According to study results, a higher adherence to the MD was associated with a low all-cause mortality risk in an elderly Italian population.
Furbatto M, Lelli D, Antonelli Incalzi R, Pedone C Nutrients. 2024; 16(22).
PMID: 39599734 PMC: 11597443. DOI: 10.3390/nu16223947.
Chen Y, Gao Y, Chen Y, Wang Z, Xu H, Hu F Nutrients. 2024; 16(11).
PMID: 38892538 PMC: 11174105. DOI: 10.3390/nu16111605.
The impact of the Mediterranean diet on immune function in older adults.
Ecarnot F, Maggi S Aging Clin Exp Res. 2024; 36(1):117.
PMID: 38780713 PMC: 11116168. DOI: 10.1007/s40520-024-02753-3.
Cacciatore S, Calvani R, Marzetti E, Picca A, Coelho-Junior H, Martone A Nutrients. 2023; 15(4).
PMID: 36839385 PMC: 9959184. DOI: 10.3390/nu15041026.
Poulsen W, Christensen K, Dalgard C Arch Public Health. 2022; 80(1):161.
PMID: 35768834 PMC: 9241213. DOI: 10.1186/s13690-022-00914-2.