Evaluation of Anti- Antibodies in Hemodialysis Patients with Chronic Kidney Disease in Sari, Iran
Overview
Affiliations
Background: has worldwide distribution and is one of the most prevalent infectious agents in humans.
Objectives: The aim of this study was to determine the prevalence of anti- antibodies in hemodialysis patients with chronic kidney disease (CKD) in the hemodialysis unit of Fatemeh Zahra hospital at the Mazandaran University of Medical Sciences in Sari, Iran.
Methods: Seventy-three patients with CKD and 145 healthy volunteers were assessed for anti- (IgG, IgM, and IgA) antibodies using a conventional ELISA technique.
Results: The anti- IgG antibody was detected in 80.8% of the cases in the patient group, while 31.5% of the cases in the CKD patient group and 31.8% in the control group were found to be positive for the anti- IgA antibody. All the patients in the CKD group were negative for the anti- IgM antibody, although 2.76% of the healthy volunteers were found to be positive. The present study suggests that there was no significant difference between the hemodialysis patient group and the healthy volunteers.
Conclusions: The epidemiological data collected in this study could serve as a reference for future studies and may be useful in developing preventive and educational strategies, and consequently reducing healthcare expenditure.
Sarmadian H, Shojapour M, Chegeni F, Tabatabaiefar M, Haghverdi F, Sarmadian R Trop Med Health. 2025; 53(1):7.
PMID: 39810270 PMC: 11730123. DOI: 10.1186/s41182-024-00676-3.
Foroutan M, Rostami A, Majidiani H, Riahi S, Khazaei S, Badri M Epidemiol Health. 2018; 40:e2018016.
PMID: 29748456 PMC: 6060338. DOI: 10.4178/epih.e2018016.