Article: A serological study on Toxoplasma gondii infection among people in south of Tehran, Iran

Although Toxoplasma gondii infection generally shows subclinical courses in adults, it may have severe pathologic effects on the fetus. For a survey of toxoplasmosis in Shahr-e-Rey area, south of Tehran, Iran, we conducted a serological study on 1,187 general populations using indirect fluorescent antibody (IFA) test. In this cross sectional study, cases were selected randomly by a local primary health care (PHC) system. Blood samples were collected in microcapillary tubes and sera were examined by IFA after centrifugation. It has been shown that 68.3% of cases in all age groups had IFA titer of 1 : 10 and higher, which we consider as positive cases, and the rate for 1 : 400 or over was 30.2%. There was meaningful correlation between anti-Toxoplasma antibody titers and age, sex, and occupation of subjected people (P < 0.05%). The incidence was higher in females and highest in the children age group (10-14 years old). The present study demonstrates high prevalence of Toxoplasma infection among the people in south of Tehran, Iran.

Citing Articles

The Relationship of Latent Toxoplasmosis and Cigarette Smoking: Seroprevalence, Risk Factor, and Case-Control Study in Fars Province, Southern Iran.

Bahreini M, Jahromi S, Radfar A, Salemi A, Dastan N, Asgari Q Pathogens. 2022; 11(11).

PMID: 36365025 PMC: 9696781. DOI: 10.3390/pathogens11111274.

Evaluation of infection in western Iran: seroepidemiology and risk factors analysis.

Mousavi-Hasanzadeh M, Sarmadian H, Ghasemikhah R, Didehdar M, Shahdoust M, Maleki M Trop Med Health. 2020; 48:35.

PMID: 32467660 PMC: 7236115. DOI: 10.1186/s41182-020-00222-x.

Seroepidemiological evaluation of immunity among the general population in southwest of Iran.

Soltani S, Foroutan M, Afshari H, Hezarian M, Kahvaz M J Parasit Dis. 2018; 42(4):636-642.

PMID: 30538365 PMC: 6261153. DOI: 10.1007/s12639-018-1047-2.

Seroepidemiological Study of Infection among Psychiatric Patients in Mashhad, Northeast of Iran.

Abdollahian E, Shafiei R, Mokhber N, Kalantar K, Fata A Iran J Parasitol. 2017; 12(1):117-122.

PMID: 28761468 PMC: 5522687.

Evaluation of Anti- Antibodies in Hemodialysis Patients with Chronic Kidney Disease in Sari, Iran.

Seyyedpour S, Afshar P, Barzegarnejad A, Kalhori S, Agah R Nephrourol Mon. 2016; 8(6):e40182.

PMID: 27896240 PMC: 5120252. DOI: 10.5812/numonthly.40182.

References

1.

Flegr J, Lindova J, Kodym P . Sex-dependent toxoplasmosis-associated differences in testosterone concentration in humans. Parasitology. 2008; 135(4):427-31. DOI: 10.1017/S0031182007004064. View

2.

Assmar M, Amirkhani A, Piazak N, Hovanesian A, Kooloobandi A, Etessami R . [Toxoplasmosis in Iran. Results of a seroepidemiological study]. Bull Soc Pathol Exot. 1997; 90(1):19-21. View

3.

Hershey D, McGregor J . Low prevalence of Toxoplasma infection in a Rocky Mountain prenatal population. Obstet Gynecol. 1987; 70(6):900-2. View

4.

Jones J, Muccioli C, Belfort Jr R, Holland G, Roberts J, Silveira C . Recently acquired Toxoplasma gondii infection, Brazil. Emerg Infect Dis. 2006; 12(4):582-7. PMC: 3294697. DOI: 10.3201/eid1204.051081. View

5.

Ghorbani M, Edrissian G, Afshar A . Serological survey of human toxoplasmosis in mountainous regions of the north-west and south-west parts of Iran (1976-77). Trans R Soc Trop Med Hyg. 1981; 75(1):38-40. DOI: 10.1016/0035-9203(81)90011-0. View

A Serological Study on Toxoplasma Gondii Infection Among People in South of Tehran, Iran