Seroprevalence of Toxoplasma Gondii Infection and Characteristics of Seropositive Patients in General Hospitals in Daejeon, Korea

Overview

Journal Korean J Parasitol

Specialty Parasitology

Date 2009 Jun 3

PMID 19488418

Citations 37

Authors

Dae-Whan Shin

Dong-Yeub Cha

Quan Juan Hua

Guang-Ho Cha

Young-Ha Lee

Affiliations

Soon will be listed here.

Abstract

To figure out the epidemiological status and relevance with other diseases in toxoplasmosis, we checked serum IgG antibody titers of 1,265 patients and medical records of seropositive patients. Seropositive rates were 6.6% by latex agglutination test (LAT) and 6.7% by ELISA. No significant differences were detected between sexes and age groups. The peak seroprevalence was detected in the 40-49-year-old age group. According to clinical department, Toxoplasma-positive rates were high in patients in psychiatry, ophthalmology, health management, emergency medicine, and thoracic surgery. Major coincidental diseases in seropositive cases were malignant neoplasms, diabetes mellitus, arthritis, chronic hepatitis B, chronic renal diseases, schizophrenia, and acute lymphadenitis, in the order of frequency. In particular, some patients with chronic hepatitis B and malignant neoplasms had high antibody titers. These results revealed that the seroprevalence of toxoplasmosis in a general hospital-based study was similar to that in a community-based study, and T. gondii seropositivity may be associated with neoplasms, diabetes, and other chronic infections.

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