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Juicebox Provides a Visualization System for Hi-C Contact Maps with Unlimited Zoom

Overview
Journal Cell Syst
Publisher Cell Press
Specialties Biology
Cell Biology
Molecular Biology
Date 2016 Jul 29
PMID 27467250
Citations 953
Authors
Neva C Durand
James T Robinson
Muhammad S Shamim
Ido Machol
Jill P Mesirov
Eric S Lander
Erez Lieberman Aiden
Affiliations
Soon will be listed here.
Abstract

Hi-C experiments study how genomes fold in 3D, generating contact maps containing features as small as 20 bp and as large as 200 Mb. Here we introduce Juicebox, a tool for exploring Hi-C and other contact map data. Juicebox allows users to zoom in and out of Hi-C maps interactively, just as a user of Google Earth might zoom in and out of a geographic map. Maps can be compared to one another, or to 1D tracks or 2D feature sets.

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