MR Imaging Biomarkers in Oncology Clinical Trials

Overview

Journal Magn Reson Imaging Clin N Am

Specialty Radiology

Date 2015 Nov 29

PMID 26613873

Citations 19

Authors

Richard G Abramson

Lori R Arlinghaus

Adrienne N Dula

C Chad Quarles

Ashley M Stokes

Jared A Weis

Jennifer G Whisenant

Eduard Y Chekmenev

Igor Zhukov

Jason M Williams

Thomas E Yankeelov

Affiliations

Soon will be listed here.

Abstract

The authors discuss eight areas of quantitative MR imaging that are currently used (RECIST, DCE-MR imaging, DSC-MR imaging, diffusion MR imaging) in clinical trials or emerging (CEST, elastography, hyperpolarized MR imaging, multiparameter MR imaging) as promising techniques in diagnosing cancer and assessing or predicting response of cancer to therapy. Illustrative applications of the techniques in the clinical setting are summarized before describing the current limitations of the methods.

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