Concise Review: Sowing the Seeds of a Fruitful Harvest: Hematopoietic Stem Cell Mobilization

Overview

Journal Stem Cells

Publisher Oxford University Press

Specialties Cell Biology
Reproductive Medicine

Date 2013 Oct 15

PMID 24123398

Citations 17

Authors

Jonathan Hoggatt

Jennifer M Speth

Louis M Pelus

Affiliations

Soon will be listed here.

Abstract

Hematopoietic stem cell transplantation is the only curative option for a number of malignant and nonmalignant diseases. As the use of hematopoietic transplant has expanded, so too has the source of stem and progenitor cells. The predominate source of stem and progenitors today, particularly in settings of autologous transplantation, is mobilized peripheral blood. This review will highlight the historical advances which led to the widespread use of peripheral blood stem cells for transplantation, with a look toward future enhancements to mobilization strategies.

Citing Articles

Plerixafor and granulocyte colony stimulating factor for poor mobilizers in patients undergoing autologous peripheral hematopoietic stem cell transplantation: Single institution study.

El Cheikh J, Terro K, El Warrak S, Ghaoui N, Sharrouf L, Timonian M Front Transplant. 2024; 1:1017579.

PMID: 38994380 PMC: 11235346. DOI: 10.3389/frtra.2022.1017579.

Role of Neurotransmitters in Steady State Hematopoiesis, Aging, and Leukemia.

Beeraka N, Basappa B, Nikolenko V, Mahesh P Stem Cell Rev Rep. 2024; 21(1):2-27.

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Kitawi R, Ledger S, Kelleher A, Ahlenstiel C Int J Mol Sci. 2024; 25(5).

PMID: 38474018 PMC: 10931721. DOI: 10.3390/ijms25052771.

Meloxicam with Filgrastim may Reduce Oxidative Stress in Hematopoietic Progenitor Cells during Mobilization of Autologous Peripheral Blood Stem Cells in Patients with Multiple Myeloma.

Patterson A, Zhang S, Liu L, Li H, Singh P, Liu Y Stem Cell Rev Rep. 2021; 17(6):2124-2138.

PMID: 34510361 DOI: 10.1007/s12015-021-10259-y.

Heme Oxygenase 1 (HO-1) as an Inhibitor of Trafficking of Normal and Malignant Hematopoietic Stem Cells - Clinical and Translational Implications.

Ratajczak M, Adamiak M, Ratajczak J, Kucia M Stem Cell Rev Rep. 2020; 17(3):821-828.

PMID: 33196976 PMC: 8166705. DOI: 10.1007/s12015-020-10083-w.

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