Radiation Dose Reduction in Computed Tomography: Techniques and Future Perspective

Overview

Journal Imaging Med

Specialty Radiology

Date 2012 Feb 7

PMID 22308169

Citations 112

Authors

Lifeng Yu

Xin Liu

Shuai Leng

James M Kofler

Juan C Ramirez-Giraldo

Mingliang Qu

Jodie Christner

Joel G Fletcher

Cynthia H McCollough

Affiliations

Soon will be listed here.

Abstract

Despite universal consensus that computed tomography (CT) overwhelmingly benefits patients when used for appropriate indications, concerns have been raised regarding the potential risk of cancer induction from CT due to the exponentially increased use of CT in medicine. Keeping radiation dose as low as reasonably achievable, consistent with the diagnostic task, remains the most important strategy for decreasing this potential risk. This article summarizes the general technical strategies that are commonly used for radiation dose management in CT. Dose-management strategies for pediatric CT, cardiac CT, dual-energy CT, CT perfusion and interventional CT are specifically discussed, and future perspectives on CT dose reduction are presented.

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References

Flohr T, Schoepf U, Ohnesorge B . Chasing the heart: new developments for cardiac CT. J Thorac Imaging. 2007; 22(1):4-16. DOI: 10.1097/RTI.0b013e318032132c. View

Hohl C, Suess C, Wildberger J, Honnef D, Das M, Muhlenbruch G . Dose reduction during CT fluoroscopy: phantom study of angular beam modulation. Radiology. 2008; 246(2):519-25. DOI: 10.1148/radiol.2462061968. View

Primak A, Fletcher J, Vrtiska T, Dzyubak O, Lieske J, Jackson M . Noninvasive differentiation of uric acid versus non-uric acid kidney stones using dual-energy CT. Acad Radiol. 2007; 14(12):1441-7. PMC: 2743375. DOI: 10.1016/j.acra.2007.09.016. View

Irie T, Kajitani M, Itai Y . CT fluoroscopy-guided intervention: marked reduction of scattered radiation dose to the physician's hand by use of a lead plate and an improved I-I device. J Vasc Interv Radiol. 2001; 12(12):1417-21. DOI: 10.1016/s1051-0443(07)61701-1. View

Noo F, Clackdoyle R, Pack J . A two-step Hilbert transform method for 2D image reconstruction. Phys Med Biol. 2004; 49(17):3903-23. DOI: 10.1088/0031-9155/49/17/006. View

La Riviere P . Penalized-likelihood sinogram smoothing for low-dose CT. Med Phys. 2005; 32(6):1676-83. DOI: 10.1118/1.1915015. View

. The 2007 Recommendations of the International Commission on Radiological Protection. ICRP publication 103. Ann ICRP. 2007; 37(2-4):1-332. DOI: 10.1016/j.icrp.2007.10.003. View

Wang G, Snyder D, OSullivan J, Vannier M . Iterative deblurring for CT metal artifact reduction. IEEE Trans Med Imaging. 1996; 15(5):657-64. DOI: 10.1109/42.538943. View

Sidky E, Pan X . Image reconstruction in circular cone-beam computed tomography by constrained, total-variation minimization. Phys Med Biol. 2008; 53(17):4777-807. PMC: 2630711. DOI: 10.1088/0031-9155/53/17/021. View

10.

Katada K, Kato R, ANNO H, Ogura Y, Koga S, Ida Y . Guidance with real-time CT fluoroscopy: early clinical experience. Radiology. 1996; 200(3):851-6. DOI: 10.1148/radiology.200.3.8756943. View

11.

Kachelriess M, Knaup M, Bockenbach O . Hyperfast parallel-beam and cone-beam backprojection using the cell general purpose hardware. Med Phys. 2007; 34(4):1474-86. DOI: 10.1118/1.2710328. View

12.

Marano R, Liguori C, Rinaldi P, Storto M, Politi M, Savino G . Coronary artery bypass grafts and MDCT imaging: what to know and what to look for. Eur Radiol. 2007; 17(12):3166-78. DOI: 10.1007/s00330-007-0722-y. View

13.

Dugdale P, Miles K, Bunce I, Kelley B, Leggett D . CT measurement of perfusion and permeability within lymphoma masses and its ability to assess grade, activity, and chemotherapeutic response. J Comput Assist Tomogr. 1999; 23(4):540-7. DOI: 10.1097/00004728-199907000-00010. View

14.

Siegel M, Schmidt B, Bradley D, Suess C, Hildebolt C . Radiation dose and image quality in pediatric CT: effect of technical factors and phantom size and shape. Radiology. 2004; 233(2):515-22. DOI: 10.1148/radiol.2332032107. View

15.

Beekma F, Kamphuis C . Ordered subset reconstruction for x-ray CT. Phys Med Biol. 2001; 46(7):1835-44. DOI: 10.1088/0031-9155/46/7/307. View

16.

Brenner D . It is time to retire the computed tomography dose index (CTDI) for CT quality assurance and dose optimization. For the proposition. Med Phys. 2006; 33(5):1189-90. DOI: 10.1118/1.2173933. View

17.

Mayo J, Whittall K, Leung A, Hartman T, Park C, Primack S . Simulated dose reduction in conventional chest CT: validation study. Radiology. 1997; 202(2):453-7. DOI: 10.1148/radiology.202.2.9015073. View

18.

Wang J, Li T, Lu H, Liang Z . Penalized weighted least-squares approach to sinogram noise reduction and image reconstruction for low-dose X-ray computed tomography. IEEE Trans Med Imaging. 2006; 25(10):1272-83. PMC: 1619874. DOI: 10.1109/42.896783. View

19.

Scheffel H, Stolzmann P, Frauenfelder T, Schertler T, Desbiolles L, Leschka S . Dual-energy contrast-enhanced computed tomography for the detection of urinary stone disease. Invest Radiol. 2007; 42(12):823-9. DOI: 10.1097/RLI.0b013e3181379bac. View

20.

Supanich M, Tao Y, Nett B, Pulfer K, Hsieh J, Turski P . Radiation dose reduction in time-resolved CT angiography using highly constrained back projection reconstruction. Phys Med Biol. 2009; 54(14):4575-93. PMC: 2931802. DOI: 10.1088/0031-9155/54/14/013. View