The Development and Application of Optogenetics

Overview

Journal Annu Rev Neurosci

Specialty Neurology

Date 2011 Jun 23

PMID 21692661

Citations 774

Authors

Lief Fenno

Ofer Yizhar

Karl Deisseroth

Affiliations

Soon will be listed here.

Abstract

Genetically encoded, single-component optogenetic tools have made a significant impact on neuroscience, enabling specific modulation of selected cells within complex neural tissues. As the optogenetic toolbox contents grow and diversify, the opportunities for neuroscience continue to grow. In this review, we outline the development of currently available single-component optogenetic tools and summarize the application of various optogenetic tools in diverse model organisms.

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