Gestational Diabetes Mellitus

Overview

Journal J Clin Invest

Specialty General Medicine

Date 2005 Mar 15

PMID 15765129

Citations 354

Authors

Thomas A Buchanan

Anny H Xiang

Affiliations

Soon will be listed here.

Abstract

Gestational diabetes mellitus (GDM) is defined as glucose intolerance of various degrees that is first detected during pregnancy. GDM is detected through the screening of pregnant women for clinical risk factors and, among at-risk women, testing for abnormal glucose tolerance that is usually, but not invariably, mild and asymptomatic. GDM appears to result from the same broad spectrum of physiological and genetic abnormalities that characterize diabetes outside of pregnancy. Indeed, women with GDM are at high risk for having or developing diabetes when they are not pregnant. Thus, GDM provides a unique opportunity to study the early pathogenesis of diabetes and to develop interventions to prevent the disease.

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