Thomas A Buchanan
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Explore the profile of Thomas A Buchanan including associated specialties, affiliations and a list of published articles.
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145
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14401
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Recent Articles
1.
Orechwa A, Abhat A, Amezcua L, Boden-Albala B, Buchanan T, Chen S, et al.
Learn Health Syst
. 2024 Jul;
8(3):e10442.
PMID: 39036535
Introduction: This article provides an overview of presentations and discussions from the inaugural Healthcare Delivery Science: Innovation and Partnerships for Health Equity Research (DESCIPHER) Symposium. Methods: The symposium brought together...
2.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
Nature
. 2024 Feb;
627(8003):347-357.
PMID: 38374256
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes and molecular mechanisms that are often specific to cell type. Here, to characterize the genetic contribution...
3.
Williamson A, Norris D, Yin X, Broadaway K, Moxley A, Vadlamudi S, et al.
Nat Genet
. 2023 Jun;
55(6):973-983.
PMID: 37291194
Distinct tissue-specific mechanisms mediate insulin action in fasting and postprandial states. Previous genetic studies have largely focused on insulin resistance in the fasting state, where hepatic insulin action dominates. Here...
4.
Suzuki K, Hatzikotoulas K, Southam L, Taylor H, Yin X, Lorenz K, et al.
medRxiv
. 2023 Apr;
PMID: 37034649
Type 2 diabetes (T2D) is a heterogeneous disease that develops through diverse pathophysiological processes. To characterise the genetic contribution to these processes across ancestry groups, we aggregate genome-wide association study...
5.
Fernandez-Rhodes L, Graff M, Buchanan V, Justice A, Highland H, Guo X, et al.
HGG Adv
. 2022 Oct;
4(1):100149.
PMID: 36268164
[This corrects the article DOI: 10.1016/j.xhgg.2022.100099.].
6.
Utzschneider K, Ehrmann D, Arslanian S, Barengolts E, Buchanan T, Caprio S, et al.
Obesity (Silver Spring)
. 2022 Jul;
30(8):1579-1588.
PMID: 35894078
Objective: The extent to which weight loss contributes to increases in insulin sensitivity (IS) and β-cell function after surgical or medical intervention has not been directly compared in individuals with...
7.
Mahajan A, Spracklen C, Zhang W, Ng M, Petty L, Kitajima H, et al.
Nat Genet
. 2022 May;
54(5):560-572.
PMID: 35551307
We assembled an ancestrally diverse collection of genome-wide association studies (GWAS) of type 2 diabetes (T2D) in 180,834 affected individuals and 1,159,055 controls (48.9% non-European descent) through the Diabetes Meta-Analysis...
8.
Fernandez-Rhodes L, Graff M, Buchanan V, Justice A, Highland H, Guo X, et al.
HGG Adv
. 2022 Apr;
3(2):100099.
PMID: 35399580
Hispanic/Latinos have been underrepresented in genome-wide association studies (GWAS) for anthropometric traits despite their notable anthropometric variability, ancestry proportions, and high burden of growth stunting and overweight/obesity. To address this...
9.
Reuter K, Angyan P, Le N, Buchanan T
JMIR Form Res
. 2021 Nov;
5(11):e29958.
PMID: 34842538
Background: Failure to find and attract clinical trial participants remains a persistent barrier to clinical research. Researchers increasingly complement recruitment methods with social media-based methods. We hypothesized that user-generated data...
10.
Genome-wide association study of body fat distribution traits in Hispanics/Latinos from the HCHS/SOL
Justice A, Young K, Gogarten S, Sofer T, Graff M, Love S, et al.
Hum Mol Genet
. 2021 Jun;
30(22):2190-2204.
PMID: 34165540
Central obesity is a leading health concern with a great burden carried by ethnic minority populations, especially Hispanics/Latinos. Genetic factors contribute to the obesity burden overall and to inter-population differences....