P Glycoprotein in Human Immunodeficiency Virus Type 1 Infection and Therapy

Overview

Journal Antimicrob Agents Chemother

Publisher American Society for Microbiology

Specialty Pharmacology

Date 2004 Mar 30

PMID 15047504

Citations 22

Authors

Sanjay U C Sankatsing

Jos H Beijnen

Alfred H Schinkel

Joep M A Lange

Jan M Prins

Affiliations

Soon will be listed here.

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References

Kempf D, Marsh K, Kumar G, Rodrigues A, Denissen J, McDonald E . Pharmacokinetic enhancement of inhibitors of the human immunodeficiency virus protease by coadministration with ritonavir. Antimicrob Agents Chemother. 1997; 41(3):654-60. PMC: 163767. DOI: 10.1128/AAC.41.3.654. View

Callaghan R, Berridge G, Ferry D, Higgins C . The functional purification of P-glycoprotein is dependent on maintenance of a lipid-protein interface. Biochim Biophys Acta. 1997; 1328(2):109-24. DOI: 10.1016/s0005-2736(97)00079-5. View

Hollt V, Kouba M, Dietel M, Vogt G . Stereoisomers of calcium antagonists which differ markedly in their potencies as calcium blockers are equally effective in modulating drug transport by P-glycoprotein. Biochem Pharmacol. 1992; 43(12):2601-8. DOI: 10.1016/0006-2952(92)90149-d. View

Dey S, Ramachandra M, Pastan I, Gottesman M, Ambudkar S . Evidence for two nonidentical drug-interaction sites in the human P-glycoprotein. Proc Natl Acad Sci U S A. 1997; 94(20):10594-9. PMC: 23414. DOI: 10.1073/pnas.94.20.10594. View

Nakamura Y, Ikeda S, Furukawa T, Sumizawa T, Tani A, Akiyama S . Function of P-glycoprotein expressed in placenta and mole. Biochem Biophys Res Commun. 1997; 235(3):849-53. DOI: 10.1006/bbrc.1997.6855. View

Mocroft A, Vella S, Benfield T, Chiesi A, Miller V, Gargalianos P . Changing patterns of mortality across Europe in patients infected with HIV-1. EuroSIDA Study Group. Lancet. 1998; 352(9142):1725-30. DOI: 10.1016/s0140-6736(98)03201-2. View

Chun T, Stuyver L, Mizell S, Ehler L, Mican J, Baseler M . Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc Natl Acad Sci U S A. 1997; 94(24):13193-7. PMC: 24285. DOI: 10.1073/pnas.94.24.13193. View

Lucia M, Cauda R, Malorni W, Rainaldi G, Tumbarello M, Tacconelli E . P-170 glycoprotein (P-170) is involved in the impairment of natural killer cell-mediated cytotoxicity in HIV+ patients. Immunol Lett. 1995; 47(3):223-6. DOI: 10.1016/0165-2478(95)00090-3. View

Brenner B, Dascal A, Margolese R, Wainberg M . Natural killer cell function in patients with acquired immunodeficiency syndrome and related diseases. J Leukoc Biol. 1989; 46(1):75-83. DOI: 10.1002/jlb.46.1.75. View

10.

Greenberger L, Lisanti C, Silva J, Horwitz S . Domain mapping of the photoaffinity drug-binding sites in P-glycoprotein encoded by mouse mdr1b. J Biol Chem. 1991; 266(31):20744-51. View

11.

van Praag R, Weverling G, Portegies P, Jurriaans S, Zhou X, Sommadossi J . Enhanced penetration of indinavir in cerebrospinal fluid and semen after the addition of low-dose ritonavir. AIDS. 2000; 14(9):1187-94. DOI: 10.1097/00002030-200006160-00016. View

12.

Schinkel A, Wagenaar E, Mol C, van Deemter L . P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs. J Clin Invest. 1996; 97(11):2517-24. PMC: 507337. DOI: 10.1172/JCI118699. View

13.

Hyafil F, Vergely C, du Vignaud P, Grand-Perret T . In vitro and in vivo reversal of multidrug resistance by GF120918, an acridonecarboxamide derivative. Cancer Res. 1993; 53(19):4595-602. View

14.

Dale I, Tuffley W, Callaghan R, Holmes J, Martin K, LUSCOMBE M . Reversal of P-glycoprotein-mediated multidrug resistance by XR9051, a novel diketopiperazine derivative. Br J Cancer. 1998; 78(7):885-92. PMC: 2063130. DOI: 10.1038/bjc.1998.597. View

15.

Tsuruo T, Iida H, Nojiri M, Tsukagoshi S, Sakurai Y . Circumvention of vincristine and Adriamycin resistance in vitro and in vivo by calcium influx blockers. Cancer Res. 1983; 43(6):2905-10. View

16.

Alaoui-Jamali M, Schecter R, Rustum Y, Centurioni M, Lehnert S, Batist G . In vivo reversal of doxorubicin resistance by a new tiapamil analog Ro11-2933. J Pharmacol Exp Ther. 1993; 264(3):1299-304. View

17.

Gollapudi S, Gupta S . Human immunodeficiency virus I-induced expression of P-glycoprotein. Biochem Biophys Res Commun. 1990; 171(3):1002-7. DOI: 10.1016/0006-291x(90)90783-j. View

18.

Clayette P, Jorajuria S, Dormont D . Significance of P-glycoprotein for the pharmacology and clinical use of HIV protease inhibitors. AIDS. 2000; 14(3):235-6. DOI: 10.1097/00002030-200002180-00004. View

19.

Chang K, Kim J, Yoo N, Kim W, Park J, Choi I . Restoration of P-glycoprotein function is involved in the increase of natural killer activity with exogenous interleukin-15 in human immunodeficiency virus-infected individuals. Yonsei Med J. 2000; 41(5):600-6. DOI: 10.3349/ymj.2000.41.5.600. View

20.

Thiebaut F, Tsuruo T, Hamada H, Gottesman M, Pastan I, Willingham M . Immunohistochemical localization in normal tissues of different epitopes in the multidrug transport protein P170: evidence for localization in brain capillaries and crossreactivity of one antibody with a muscle protein. J Histochem Cytochem. 1989; 37(2):159-64. DOI: 10.1177/37.2.2463300. View