Investigational New Drugs
Overview
Investigational New Drugs is a peer-reviewed scientific journal that focuses on the development and evaluation of novel therapeutic agents for the treatment of various diseases. It publishes cutting-edge research articles, reviews, and clinical trials, providing valuable insights into the discovery and development of innovative drugs. The journal serves as a platform for researchers, clinicians, and pharmaceutical professionals to share their findings and contribute to the advancement of drug discovery and development.
Details
Details
Abbr.
Invest New Drugs
Publisher
Springer
Start
1983
End
Continuing
Frequency
Quarterly
p-ISSN
0167-6997
e-ISSN
1573-0646
Country
United States
Language
English
Specialty
Oncology
Metrics
Metrics
h-index / Ranks: 3275
97
SJR / Ranks: 3293
1086
CiteScore / Ranks: 3060
6.80
JIF / Ranks: 2884
3.4
Recent Articles
21.
Taniguchi Y, Tamiya A, Osuga M, Isa S, Nakamura K, Mizumori Y, et al.
Invest New Drugs
. 2025 Jan;
43(1):101-107.
PMID: 39789369
The impact of clinical stage on the effectiveness of osimertinib for epidermal growth factor receptor (EGFR) mutation-positive non-small cell lung cancer (NSCLC) remains unexamined. We investigated osimertinib therapeutic efficacy variation...
22.
Shimomura K, Ogata T, Maeda A, Narita Y, Taniguchi H, Murotani K, et al.
Invest New Drugs
. 2025 Jan;
43(1):118-125.
PMID: 39789368
Anamorelin, a highly selective ghrelin receptor agonist, enhances appetite and increases lean body mass in patients with cancer cachexia. However, the predictors of its therapeutic effectiveness are uncertain. This study...
23.
Li M, Wang X, Gong J, Lu H
Invest New Drugs
. 2025 Jan;
43(1):108-117.
PMID: 39786663
A novel molecular classification for small cell lung cancer (SCLC) has been established utilizing the transcription factors achaete-scute homologue 1 (ASCL1), neurogenic differentiation factor 1 (NeuroD1), POU class 2 homeobox...
24.
Yu Z, Leng B, You R, Wang C, Diao L, Xu Q, et al.
Invest New Drugs
. 2025 Jan;
43(1):93-100.
PMID: 39762642
Purpose: The combination therapy of lenvatinib and immunotherapy as first-line treatment remains controversial in unresectable hepatocellular carcinoma (uHCC). This research aimed to compare the efficacy and safety of lenvatinib monotherapy...
25.
Liu R, Ji Z, Wang X, Xin J, Zhu L, Ge S, et al.
Invest New Drugs
. 2025 Jan;
43(1):81-92.
PMID: 39760815
Pancreatic cancer patients urgently need new treatments, and we explored the efficacy and safety of combination therapy with AL2846 and gemcitabine in pancreatic cancer patients. This was a single-arm, single-center,...
26.
Wu Z, Li X, Huang R, He B, Wang C
Invest New Drugs
. 2025 Jan;
43(1):74-80.
PMID: 39752075
The understanding of pembrolizumab-induced Stevens-Johnson syndrome (SJS) /toxic epidermal necrolysis (TEN) primarily derives from case reports, leaving specific clinical features largely unknown. This study aims to investigate the clinical characteristics...
27.
Damaj N, Nassar D, Chamaa B, Kattan J
Invest New Drugs
. 2025 Jan;
43(1):69-73.
PMID: 39747775
Thymomas and thymic carcinomas are the most prevalent tumors that develop in the thymus's epithelial tissue. Thymomas are malignant tumors that develop from the epithelial cells of the thymus and...
28.
Boland P, Lenz H, Ciombor K, Florou V, Pishvaian M, Cusnir M, et al.
Invest New Drugs
. 2024 Dec;
43(1):60-68.
PMID: 39725778
Antiangiogenic drugs may cause vascular normalization and correct hypoxia in tumors, shifting cells to mitochondrial respiration as the primary source of energy. In turn, the addition of an inhibitor of...
29.
Sun Y, Wei L, Liu H, Zong G, Xia Z, Li X, et al.
Invest New Drugs
. 2024 Dec;
43(1):50-59.
PMID: 39725777
Melanoma, one of the most prevalent cancers worldwide, frequently metastasizes to the lung and bones. Tumor-associated macrophages play essential roles in melanoma metastasis but the underlying mechanism remains obscure. We...
30.
Zhao S, Sun W, Sun J, Peng L, Wang C
Invest New Drugs
. 2024 Dec;
43(1):42-49.
PMID: 39724319
Psoriasis is an uncommon immune-mediated adverse event linked to nivolumab, and its clinical characteristics remain inadequately defined. This study aims to investigate the clinical features and patterns of nivolumab-induced psoriasis,...