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Clinical Reviews in Allergy & Immunology

Clinical Reviews in Allergy & Immunology is a scholarly journal that provides comprehensive and up-to-date reviews on various aspects of allergy and immunology. It covers a wide range of topics including allergic diseases, immunodeficiencies, autoimmune disorders, and immunotherapy. With a focus on clinical relevance, this journal serves as a valuable resource for healthcare professionals, researchers, and students in the field of allergy and immunology.

Details
Abbr. Clin Rev Allergy Immunol
Start 1995
End Continuing
Frequency Bimonthly, <2001->
p-ISSN 1080-0549
e-ISSN 1559-0267
Country United States
Language English
Metrics
h-index / Ranks: 3170 99
SJR / Ranks: 1021 2195
CiteScore / Ranks: 356 19.90
JIF / Ranks: 545 9.1
Recent Articles
1.
Xu L, Shen T, Li Y, Wu X
Clin Rev Allergy Immunol . 2025 Mar; 68(1):29. PMID: 40085180
N6-methyladenosine (mA), a prevalent and essential RNA modification, serves a key function in driving autoimmune disease pathogenesis. By modulating immune cell development, activation, migration, and polarization, as well as inflammatory...
2.
Wu X, Liu C, Zhang C, Kuai L, Hu S, Jia N, et al.
Clin Rev Allergy Immunol . 2025 Mar; 68(1):28. PMID: 40080284
Historically, lactate has been considered merely a metabolic byproduct. However, recent studies have revealed that lactate plays a much more dynamic role, acting as an immune signaling molecule that influences...
3.
Zhang J, Shen M
Clin Rev Allergy Immunol . 2025 Mar; 68(1):27. PMID: 40074883
Interleukin (IL)-17, a pro-inflammatory cytokine, plays a pivotal role in immune regulation by bridging innate and adaptive responses. Beyond its canonical involvement in T helper-17 cells-mediated immunity, IL-17 contributes significantly...
4.
Zong Y, Tong X, Chong W
Clin Rev Allergy Immunol . 2025 Mar; 68(1):26. PMID: 40072803
Uveitis involves a complex interplay of immune cell infiltration and cytokine imbalances, with Th17 cells playing a central role in this process. Th17 cells contribute to disease pathogenesis by promoting...
5.
Qin H, Xiao X, Xue P, Qin D, Wang S, Li Y, et al.
Clin Rev Allergy Immunol . 2025 Mar; 68(1):25. PMID: 40064711
The pathology of urticaria is complex. Recently, researchers have widely focused on the role that the coagulation/fibrinolysis system plays in the pathology of urticaria. The potential of coagulation/fibrinolysis biomarkers as...
6.
Zuraw B, Bork K, Bouillet L, Christiansen S, Farkas H, Germenis A, et al.
Clin Rev Allergy Immunol . 2025 Mar; 68(1):24. PMID: 40053270
Hereditary angioedema (HAE) has been recognized for almost 150 years. The newest form of HAE, where C1 inhibitor levels are normal (HAE-nC1INH), was first described in 2000. Over the last...
7.
Purow J, Waidner L, Ale H
Clin Rev Allergy Immunol . 2025 Mar; 68(1):23. PMID: 40038168
22q11.2 deletion and duplication syndromes are complex genetic syndromes composed of a wide spectrum of clinical manifestations, mostly affecting cardiovascular, endocrine, neurodevelopmental, and immune functioning. 22q11.2 deletion syndrome (22q11.2 DS)...
8.
Xiao Y, Zhang Y, Deng S, Yang X, Yao X
Clin Rev Allergy Immunol . 2025 Mar; 68(1):22. PMID: 40024940
Androgenetic alopecia (AGA), a leading cause of progressive hair loss, affects up to 50% of males aged 50 years, causing significant psychological burden. Current treatments, such as anti-androgen drugs and...
9.
Li L, He Y, Zhao J, Yin H, Feng X, Fan X, et al.
Clin Rev Allergy Immunol . 2025 Feb; 68(1):21. PMID: 39982546
Autoimmune diseases are characterized by immune dysregulation, resulting in aberrant reactivity of T cells and antibodies to self-antigens, leading to various patterns of inflammation and organ dysfunction. However, current therapeutic...
10.
Elieh-Ali-Komi D, Shafaghat F, Alipoor S, Kazemi T, Atiakshin D, Pyatilova P, et al.
Clin Rev Allergy Immunol . 2025 Feb; 68(1):20. PMID: 39976807
Mast cells (MCs) communicate with other cells by direct cell-to-cell interaction, secreting mediators, and releasing exosomes (EXOs). MC-exosomes (MC-EXOs) contain proteins, lipids, mRNAs, and noncoding RNAs (ncRNAs), exhibit typical EXO...