Zsolt Ruzsics
Overview
Explore the profile of Zsolt Ruzsics including associated specialties, affiliations and a list of published articles.
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89
Citations
2870
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Recent Articles
1.
Ziu T, Sambur E, Ruzsics Z, Hengel H, Grabherr R, Hofinger S, et al.
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39408791
The synthetic peptide TAT-I24 (GRKKRRQRRRPPQCLAFYACFC) exerts antiviral activity against several double-stranded (ds) DNA viruses, including herpes simplex viruses, cytomegalovirus, some adenoviruses, vaccinia virus and SV40 polyomavirus. In the present study,...
2.
Hildenbrand A, Cramer P, Bertolotti M, Kaiser N, Klasener K, Nickel C, et al.
Front Immunol
. 2024 Aug;
15:1432226.
PMID: 39139562
Introduction: The early transcription unit 3 (E3) of human adenoviruses (HAdVs) encodes several immunoevasins, including the E3/49K protein, which is unique for species D of HAdVs. It is expressed as...
3.
Riedl A, Bojkova D, Tan J, Jeney A, Larsen P, Jeney C, et al.
Vaccines (Basel)
. 2024 Jul;
12(7).
PMID: 39066429
We investigated the basic characteristics of a new murine cytomegalovirus (MCMV) vector platform. Using BAC technology, we engineered replication-competent recombinant MCMVs with deletions of up to 26% of the wild-type...
4.
Fischer J, Fedotova A, Buhler C, Darriba L, Schreiner S, Ruzsics Z
Viruses
. 2024 May;
16(5).
PMID: 38793540
Recombinant adenoviruses are widely used in clinical and laboratory applications. Despite the wide variety of available sero- and genotypes, only a fraction is utilized in vivo. As adenoviruses are a...
5.
Funk C, Uhlig N, Ruzsics Z, Baur F, Peindl M, Nietzer S, et al.
Mol Ther Oncol
. 2024 Apr;
32(1):200784.
PMID: 38596296
Viruses are able to efficiently penetrate cells, multiply, and eventually kill infected cells, release tumor antigens, and activate the immune system. Therefore, viruses are highly attractive novel agents for cancer...
6.
Fischer J, Fedotova A, Jaki L, Sallard E, Erhardt A, Fuchs J, et al.
Mol Ther Methods Clin Dev
. 2024 Apr;
32(2):101241.
PMID: 38585687
While recombinant adenoviruses (rAds) are widely used in both laboratory and medical gene transfer, library-based applications using this vector platform are not readily available. Recently, we developed a new method,...
7.
Maler M, Zwick S, Kallfass C, Engelhard P, Shi H, Hellig L, et al.
J Innate Immun
. 2024 Mar;
16(1):226-247.
PMID: 38527452
Introduction: While TLR ligands derived from microbial flora and pathogens are important activators of the innate immune system, a variety of factors such as intracellular bacteria, viruses, and parasites can...
8.
Li R, Galindo C, Davidson D, Guo H, Zhong M, Qian J, et al.
Cell Rep
. 2024 Feb;
43(3):113800.
PMID: 38386559
Infection of mice by mouse cytomegalovirus (MCMV) triggers activation and expansion of Ly49H natural killer (NK) cells, which are virus specific and considered to be "adaptive" or "memory" NK cells....
9.
Schwabenland M, Mossad O, Sievert A, Peres A, Ringel E, Baasch S, et al.
Nat Commun
. 2023 May;
14(1):2721.
PMID: 37169749
While the precise processes underlying a sex bias in the development of central nervous system (CNS) disorders are unknown, there is growing evidence that an early life immune activation can...
10.
Mahmutefendic Lucin H, Lukanovic Juric S, Marcelic M, Stimac I, Viduka I, Blagojevic Zagorac G, et al.
Viruses
. 2023 Mar;
15(3).
PMID: 36992475
Extensive reorganization of infected cells and the formation of large structures known as the nuclear replication compartment (RC) and cytoplasmic assembly compartment (AC) is a hallmark of beta-herpesvirus infection. These...