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Christian A Mohr

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Articles 8
Citations 177
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Recent Articles
1.
Mohr H, Mohr C, Schneider M, Scrivano L, Adler B, Kraner-Schreiber S, et al.
PLoS Pathog . 2012 Jun; 8(6):e1002728. PMID: 22685399
There is increasing evidence for a connection between DNA replication and the expression of adjacent genes. Therefore, this study addressed the question of whether a herpesvirus origin of replication can...
2.
Muhlbach H, Mohr C, Ruzsics Z, Koszinowski U
Viruses . 2011 Oct; 1(3):420-40. PMID: 21994555
Investigating and assigning gene functions of herpesviruses is a process, which profits from consistent technical innovation. Cloning of bacterial artificial chromosomes encoding herpesvirus genomes permits nearly unlimited possibilities in the...
3.
Maninger S, Bosse J, Lemnitzer F, Pogoda M, Mohr C, von Einem J, et al.
J Virol . 2011 Jul; 85(18):9254-67. PMID: 21715482
The gene M94 of murine cytomegalovirus (MCMV) as well as its homologues UL16 in alphaherpesviruses is involved in viral morphogenesis. For a better understanding of its role in the viral...
4.
Sacher T, Mohr C, Weyn A, Schlichting C, Koszinowski U, Ruzsics Z
Eur J Cell Biol . 2011 Apr; 91(1):70-7. PMID: 21492952
Human cytomegalovirus (HCMV) is the major viral cause of morbidity in immune compromised patients and of pre- and perinatal pathology in newborns. The clinical manifestations are highly variable and the...
5.
Scrivano L, Esterlechner J, Muhlbach H, Ettischer N, Hagen C, Grunewald K, et al.
J Virol . 2010 Feb; 84(9):4469-80. PMID: 20181688
The glycoprotein gO (UL74) of human cytomegalovirus (HCMV) forms a complex with gH/gL. Virus mutants with a deletion of gO show a defect in secondary envelopment with the consequence that...
6.
Sacher T, Podlech J, Mohr C, Jordan S, Ruzsics Z, Reddehase M, et al.
Cell Host Microbe . 2008 Apr; 3(4):263-72. PMID: 18407069
The course of systemic viral infections is determined by the virus productivity of infected cell types and the efficiency of virus dissemination throughout the host. Here, we used a cell-type-specific...
7.
Sacher T, Jordan S, Mohr C, Vidy A, Weyn A, Ruszics Z, et al.
Med Microbiol Immunol . 2008 Mar; 197(2):269-76. PMID: 18324415
Cytomegalovirus (CMV), a prototypic beta-herpesvirus, is an important human pathogen causing protean clinical manifestations in immature and immunocompromised patients. Mechanisms of infection can be studied in a mouse model. Mouse...
8.
Mohr C, Cicin-Sain L, Wagner M, Sacher T, Schnee M, Ruzsics Z, et al.
Int J Med Microbiol . 2007 Aug; 298(1-2):115-25. PMID: 17702650
The advances of sequence knowledge and genetic engineering hold a great promise for a rational approach to vaccine development. Herpesviruses are important pathogens of all vertebrates. They cause acute and...