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Ziyuan Ma

Explore the profile of Ziyuan Ma including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 746
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Recent Articles
1.
Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, et al.
Science . 2025 Feb; 387(6734):eadp4753. PMID: 39913582
Kidney dysfunction is a major cause of mortality, but its genetic architecture remains elusive. In this study, we conducted a multiancestry genome-wide association study in 2.2 million individuals and identified...
2.
Shen Y, Yang J, Ma Z, Li Y, Dong W, Duan T
Mycorrhiza . 2025 Jan; 35(1):7. PMID: 39869214
Most cold-season grasses can be colonized by belowground arbuscular mycorrhizal (AM) fungi and foliar grass endophytes (Epichloë) simultaneously while also be attacked by insect herbivores. The colonization of AM fungi...
3.
Dang R, Dalmia M, Ma Z, Jin M, Aluru K, Mirabella V, et al.
Cell Regen . 2025 Jan; 14(1):1. PMID: 39775628
Astroglia are integral to brain development and the emergence of neurodevelopmental disorders. However, studying the pathophysiology of human astroglia using brain organoid models has been hindered by inefficient astrogliogenesis. In...
4.
Ma Z, Li W, Shen Y, Xu Y, Liu G, Chang J, et al.
Nat Methods . 2024 Nov; 22(1):102-112. PMID: 39528677
Designing proteins with improved functions requires a deep understanding of how sequence and function are related, a vast space that is hard to explore. The ability to efficiently compress this...
5.
Abedini A, Levinsohn J, Klotzer K, Dumoulin B, Ma Z, Frederick J, et al.
Nat Genet . 2024 Jul; 56(8):1712-1724. PMID: 39048792
Kidneys are intricate three-dimensional structures in the body, yet the spatial and molecular principles of kidney health and disease remain inadequately understood. We generated high-quality datasets for 81 samples, including...
6.
Jin M, Ma Z, Zhang H, Papetti A, Dang R, Stillitano A, et al.
bioRxiv . 2024 Jul; PMID: 39005270
Human-mouse chimeric brain models, generated by transplanting human induced pluripotent stem cell (hiPSC)-derived neural cells, are valuable for studying the development and function of human neural cells in vivo. Understanding...
7.
Jin M, Ma Z, Dang R, Zhang H, Kim R, Xue H, et al.
bioRxiv . 2024 Apr; PMID: 38559257
While challenging, identifying individuals displaying resilience to Alzheimer's disease (AD) and understanding the underlying mechanism holds great promise for the development of new therapeutic interventions to effectively treat AD. Down...
8.
Wang H, Polara H, Bhadran A, Shah T, Babanyinah G, Ma Z, et al.
Front Pharmacol . 2024 Mar; 15:1356639. PMID: 38500763
Amphiphilic functional polycaprolactone (PCL) diblock copolymers are excellent candidates for micellar drug delivery. The functional groups on the backbone significantly affect the properties of PCL. A systematic investigation of the...
9.
Zhang S, Ma Z, Li W, Shen Y, Xu Y, Liu G, et al.
Res Sq . 2024 Mar; PMID: 38464127
Designing proteins with improved functions requires a deep understanding of how sequence and function are related, a vast space that is hard to explore. The ability to efficiently compress this...
10.
Abedini A, Sanchez-Navaro A, Wu J, Klotzer K, Ma Z, Poudel B, et al.
J Clin Invest . 2023 Oct; 134(1). PMID: 37906287
Mineralocorticoid excess commonly leads to hypertension (HTN) and kidney disease. In our study, we used single-cell expression and chromatin accessibility tools to characterize the mineralocorticoid target genes and cell types....