Zhengxiang Gu
Overview
Explore the profile of Zhengxiang Gu including associated specialties, affiliations and a list of published articles.
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28
Citations
94
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Recent Articles
11.
Zhang Y, Gu Z, Bi J, Jiao Y
Nanoscale
. 2022 Jul;
14(30):10873-10879.
PMID: 35843210
The sluggish kinetics of the oxygen evolution reaction (OER) restrains the development of water splitting technologies and the efficiency of producing sustainable resources. To this end, the introduction of iron...
12.
Zhang Y, Gu Z, Yun S, Luo K, Bi J, Jiao Y, et al.
Nanotechnology
. 2022 May;
33(34).
PMID: 35550566
Fe-based metal-organic frameworks (MOFs) are promising drug delivery materials due to their large surface area, high stability, and biocompatibility. However, their drug loading capacity is constrained by their small pore...
13.
Gu Z, Wei X, Zhang X, Duan Z, Gu Z, Gong Q, et al.
Small
. 2021 Oct;
17(47):e2104125.
PMID: 34655163
Oxygen evolution reaction (OER) is critical for optimizing renewable energy systems, including metal-air batteries and water electrolysis. One major challenge for OER is to develop durable and cost-effective electrocatalysts with...
14.
Gu Z, Chen Y, Wei Z, Qian L, Al-Enizi A, Ma J, et al.
J Colloid Interface Sci
. 2020 Jul;
580:623-629.
PMID: 32711210
The electrochemical dinitrogen reduction represents an attractive approach of converting N and water into ammonia, while the rational design of catalytic active centers remains challenging. Investigating model molecular catalysts with...
15.
Huang C, Shang L, Han P, Gu Z, Al-Enizi A, Almutairi T, et al.
J Colloid Interface Sci
. 2019 May;
552:312-318.
PMID: 31132633
The electrochemical nitrogen reduction reaction (NRR) under mild conditions is significantly challenging, due to the extremely high stability of dinitrogen (N) molecules. The NRR pathway also confronts the competitive water...
16.
Ge H, Gu Z, Han P, Shen H, Al-Enizi A, Zhang L, et al.
J Colloid Interface Sci
. 2018 Jul;
531:564-569.
PMID: 30056331
The increasing accumulation of CO in the atmosphere has been leading to serious environmental problems. Electrochemical reduction of CO is a potential means of carbon recycling for energy storage and...
17.
Shi J, Gu Z, Jurica E, Wu X, Haque L, Williams K, et al.
J Med Chem
. 2018 Jan;
61(3):681-694.
PMID: 29316397
G protein-coupled receptor 40 (GPR40) has become an attractive target for the treatment of diabetes since it was shown clinically to promote glucose-stimulated insulin secretion. Herein, we report our efforts...
18.
Ellsworth B, Sher P, Wu X, Wu G, Sulsky R, Gu Z, et al.
J Med Chem
. 2013 Nov;
56(23):9586-600.
PMID: 24182233
Several strategies have been employed to reduce the long in vivo half-life of our lead CB1 antagonist, triazolopyridazinone 3, to differentiate the pharmacokinetic profile versus the lead clinical compounds. An...
19.
Yang Y, Miller K, Zhu Y, Hong Y, Tian Y, Murugesan N, et al.
Bioorg Med Chem Lett
. 2011 Oct;
21(22):6856-60.
PMID: 21962575
Obesity remains a significant public health issue leading to Type II diabetes and cardiovascular disease. CB1 antagonists have been shown to suppress appetite and reduce body weight in animal models...
20.
Zhang H, Zhang D, Li W, Yao M, DArienzo C, Li Y, et al.
Drug Metab Dispos
. 2007 Feb;
35(5):795-805.
PMID: 17303626
2-{Butyryl-[2'-(4,5-dimethyl-isoxazol-3-ylsulfamoyl)-biphenyl-4-ylmethyl]-amino}-N-isopropyl-3-methyl-butyramide (BMS-1) is a potent dual acting angiotensin-1 and endothelin-A receptor antagonist. The compound was subject to rapid metabolic clearance in monkey and human liver microsomes and exhibited low systemic...