Zhengchen Su
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Explore the profile of Zhengchen Su including associated specialties, affiliations and a list of published articles.
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10
Citations
86
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Recent Articles
1.
Su Z, Shelite T, Qiu Y, Chang Q, Wakamiya M, Bei J, et al.
Pathogens
. 2021 Oct;
10(10).
PMID: 34684255
Introduction: Intracellular cAMP receptor exchange proteins directly activated by cAMP 1 () regulate obligate intracellular parasitic bacterium rickettsial adherence to and invasion into vascular endothelial cells (ECs). However, underlying precise...
2.
Xiao J, Zhang B, Su Z, Liu Y, Shelite T, Chang Q, et al.
J Biol Chem
. 2021 Oct;
297(5):101315.
PMID: 34678311
Coagulopathy is associated with both inflammation and infection, including infections with novel severe acute respiratory syndrome coronavirus-2, the causative agent Coagulopathy is associated with both inflammation and infection, including infection...
3.
Liu Y, Zhou C, Su Z, Chang Q, Qiu Y, Bei J, et al.
mBio
. 2021 May;
12(3).
PMID: 33975935
Spotted fever group rickettsioses (SFRs) are devastating human infections. Vascular endothelial cells (ECs) are the primary targets of rickettsial infection. Edema resulting from EC barrier dysfunction occurs in the brain...
4.
Liu Y, Garron T, Chang Q, Su Z, Zhou C, Qiu Y, et al.
Pathogens
. 2021 Apr;
10(5).
PMID: 33922476
The SARS-CoV-2 pandemic has inspired renewed interest in understanding the fundamental pathology of acute respiratory distress syndrome (ARDS) following infection. However, the pathogenesis of ARDS following SRAS-CoV-2 infection remains largely...
5.
Liu Y, Garron T, Chang Q, Su Z, Zhou C, Gong E, et al.
bioRxiv
. 2021 Jan;
PMID: 33398280
The SARS-CoV-2 pandemic has inspired renewed interest in understanding the fundamental pathology of acute respiratory distress syndrome (ARDS) following infection because fatal COVID-19 cases are commonly linked to respiratory failure...
6.
Xiao J, Zhang B, Su Z, Liu Y, Shelite T, Chang Q, et al.
bioRxiv
. 2020 Sep;
PMID: 32908983
Key Point: PI3K/eNOS pathway-mediated, inflammation-triggered vWF secretion is the target of the pharmacological manipulation of the cAMP-EPAC system.
7.
Su Z, Chang Q, Drelich A, Shelite T, Judy B, Liu Y, et al.
PLoS Negl Trop Dis
. 2020 Jul;
14(7):e0007960.
PMID: 32687500
Intracerebral microhemorrhages (CMHs) are small foci of hemorrhages in the cerebrum. Acute infections induced by some intracellular pathogens, including rickettsia, can result in CMHs. Annexin a2 (ANXA2) has been documented...
8.
Liu Y, Xiao J, Zhang B, Shelite T, Su Z, Chang Q, et al.
Lab Invest
. 2020 Apr;
100(8):1030-1041.
PMID: 32238906
Talin and vinculin, both actin-cytoskeleton-related proteins, have been documented to participate in establishing bacterial infections, respectively, as the adapter protein to mediate cytoskeleton-driven dynamics of the plasma membrane. However, little...
9.
He X, Zhang W, Chang Q, Su Z, Gong D, Zhou Y, et al.
Lab Invest
. 2019 Jun;
99(11):1650-1660.
PMID: 31253864
Understanding bacterial adhesion is challenging and critical to our understanding of the initial stages of the pathogenesis of endovascular bacterial infections. The vascular endothelial cell (EC) is the main target...
10.
He X, Drelich A, Yu S, Chang Q, Gong D, Zhou Y, et al.
Life Sci
. 2019 Feb;
221:1-12.
PMID: 30738042
Plasmin-mediated fibrinolysis at the surface of vascular endothelial cells (SVEC) plays a key role in maintaining vascular hemostasis, in which the cAMP pathway participates. After externalization to the SVEC, annexin...