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Zhenchao Wang

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Citations 139
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Recent Articles
1.
Yang L, Yang M, Wang Z, Zhao W
Angew Chem Int Ed Engl . 2025 Feb; :e202424141. PMID: 39971716
Enolates are ubiquitous intermediates in organic synthesis. Among them, boron enolates exhibit distinctive reactivity patterns and selectivities due to the presence of a boron atom, making their synthesis highly attractive....
2.
Tan H, Zhou Y, Li F, Xu C, Li C, Meng J, et al.
Bioorg Chem . 2025 Feb; 156:108221. PMID: 39914033
The percentage of people with lung cancer remains high. Given that the majority of NSCLC patients are currently on third-generation clinical agents, the search for a class of highly effective...
3.
Zhang F, Li C, Yang D, Liu B, Zhou Y, Zhou Z, et al.
Anal Chem . 2025 Jan; 97(5):3063-3073. PMID: 39869504
5-Methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC) are crucial epigenetic modifications in eukaryotic genomic DNA that regulate gene expression and are associated with the occurrence of various cancers. Here, we combined bisulfite...
4.
Shao L, Feng N, Zhou Y, Li C, Chen D, Li C, et al.
Mol Divers . 2025 Jan; PMID: 39825985
This study focuses on the design, synthesis, and evaluation of benzimidazole derivatives for their anti-tumor activity against A549 and PC-3 cells. Initial screening using the MTT assay identified compound 5m...
5.
Zhao X, Chen X, He M, Wu S, Shi Y, Luo D, et al.
Int J Biol Macromol . 2024 Dec; 290:138992. PMID: 39708853
Understanding the insecticide resistance mechanisms and their underlying regulatory pathways is essential for pest management. Previous findings indicated that the overexpression of P450 gene, CYP6ER1, was a key mechanism for...
6.
Feng N, Qiu X, Li F, Zhou Y, Li C, Liu B, et al.
Mol Divers . 2024 Dec; PMID: 39653962
Piperlongumine, a natural product from traditional Chinese medicine, shows promising antitumor effects but suffers from high toxicity. In this study, X and Q series Piperlongumine derivatives containing 1, 2, 3-triazole...
7.
Tang Y, Wang Y, Guo X, Xu Y, Wang Z, Wu J
J Agric Food Chem . 2024 Nov; 72(47):26057-26073. PMID: 39557543
Coumarin, a naturally occurring active ingredient with various biological activities in pesticides, is commonly found in plants belonging to the Rutaceae and Apiaceae families. Thanks to its unique structural properties...
8.
Wu G, Wang W, Li F, Xu C, Zhou Y, Li Z, et al.
Molecules . 2024 Nov; 29(21). PMID: 39519796
A series of β-carboline derivatives containing nitrogen heterocycles were designed and synthesized. All compounds were screened for their antitumor activity against four human tumor cell lines (A549, K562, PC-3, T47D)....
9.
Wang Z, Kushibiki H, Tarusawa T, Osonoi S, Ogasawara S, Miura C, et al.
J Neurochem . 2024 Oct; 169(2):e16235. PMID: 39453752
Diabetic polyneuropathy (DPN) is a multifactorial disease associated not only with hyperglycaemia but also with circulatory disturbances such as hypertension. A close interaction between the immune system and hypertension is...
10.
Meng J, Zhang L, Tuo X, Ding Y, Chen K, Li M, et al.
J Adv Res . 2024 Oct; PMID: 39389307
Introduction: The looming antibiotic-resistance problem has imposed an enormous crisis on global public health and agricultural development. Even worse, the evolution and widespread distribution of antibiotic-resistance elements in bacterial pathogens...