Zhefan Zhang
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Explore the profile of Zhefan Zhang including associated specialties, affiliations and a list of published articles.
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10
Citations
53
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Recent Articles
1.
Quan Q, Li Y, Zhang Z, Van der Eycken E, Cai L, Song L
Org Lett
. 2024 Dec;
27(1):482-487.
PMID: 39716031
We herein report the efficient synthesis of peptide-benzazepine conjugates from Lys-based peptides and acroleins via Rh(III)-catalyzed double C-H activation. This reaction features mild reaction conditions, broad scope, high atom and...
2.
Zhang Z, Wan T, Quan Q, Zang Y, Xu J, Tang S, et al.
Org Lett
. 2024 Dec;
26(50):10915-10920.
PMID: 39632563
Herein, we report a Rh(III)-catalyzed triple C-H activation-annulation of Phe-based peptides with alkynes for the preparation of fluorescent peptides. The robustness of this protocol is reflected by a broad substrate...
3.
He N, Hong A, Zhao K, Zhang Z, Wang S, Jia Y
Open Med (Wars)
. 2024 Jan;
19(1):20230883.
PMID: 38205152
Kashin-Beck disease (KBD) is an endemic osteochondropathy. A specific gene called SRY-box transcription factor 6 () is important for forming cartilage. This study aims to explore the potential correlation between...
4.
Wen S, Chen C, Du S, Zhang Z, Huang Y, Han Z, et al.
Org Lett
. 2017 Nov;
19(24):6474-6477.
PMID: 29164897
The t-Bu-Wudaphos was successfully applied into Rh-catalyzed asymmetric hydrogenation of α,α-disubstituted terminal olefins bearing a carboxy-directed group with excellent reactivities and enantioselectivities via the ion pair noncovalent interaction (up to...
5.
Chen C, Wen S, Geng M, Jin S, Zhang Z, Dong X, et al.
Chem Commun (Camb)
. 2017 Aug;
53(70):9785-9788.
PMID: 28816301
Upon incorporation of a noncovalent ion pair interaction, a new chiral ferrocenyl bisphosphorus ligand t-Bu-Wudaphos was developed. t-Bu-Wudaphos can be easily synthesized with very high diastereoselectivity as a highly air...
6.
Chen C, Wang H, Zhang Z, Jin S, Wen S, Ji J, et al.
Chem Sci
. 2017 Jun;
7(11):6669-6673.
PMID: 28567257
A new class of ferrocenyl chiral bisphosphorus ligand, Wudaphos, was developed, and exhibits excellent and activity ( up to 99%, TON up to 20 000) for the asymmetric hydrogenation of...
7.
Chen C, Zhang Z, Jin S, Fan X, Geng M, Zhou Y, et al.
Angew Chem Int Ed Engl
. 2017 May;
56(24):6808-6812.
PMID: 28493501
Inspired by the unique character of enzymes, we developed novel chiral SPO (secondary-phosphine-oxide) ligand (SPO-Wudaphos) which can enter into both ion pair and H-bond noncovalent interactions. The novel chiral SPO-Wudaphos...
8.
Chen C, Jin S, Zhang Z, Wei B, Wang H, Zhang K, et al.
J Am Chem Soc
. 2017 Mar;
139(11):4230.
PMID: 28281749
No abstract available.
9.
Kong D, Zhan Y, Liu Z, Ding T, Li M, Yu H, et al.
Aging Cell
. 2016 Jul;
15(6):1092-1102.
PMID: 27470296
SIRT1 has many important molecular functions in aging, and the estrogen receptors (ERs) have a vasculoprotective effect, although the detailed mechanism for the roles of SIRT1 and ERs in vascular...
10.
Chen C, Jin S, Zhang Z, Wei B, Wang H, Zhang K, et al.
J Am Chem Soc
. 2016 Jul;
138(29):9017-20.
PMID: 27385399
The first interrupted asymmetric hydroaminomethylation reaction was developed. The challenging trans-1,2-disubstituted olefins were employed as substrates, and a series of valuable chiral pyrrolidinones and pyrrolidines were obtained in high yields...