Xiu-Qin Dong
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Explore the profile of Xiu-Qin Dong including associated specialties, affiliations and a list of published articles.
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Articles
75
Citations
231
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Recent Articles
1.
Cheng X, Fu C, Chen B, Chang X, Dong X, Wang C
J Am Chem Soc
. 2025 Feb;
147(6):5014-5024.
PMID: 39893690
Current synthetic transformations occur readily with starting materials that possess both innate reactivity and steric accessibility or functional-group-oriented reactivity. However, achieving reactions with inactive feedstock substrates remains significantly challenging and...
2.
Tian K, Jin Z, Liu X, He L, Liu H, Yu P, et al.
Chem Sci
. 2024 Dec;
16(3):1233-1240.
PMID: 39677940
Developing methodologies for the expedient construction of biologically important δ-valerolactones bearing a privileged azaarene moiety and a sterically congested all-carbon quaternary stereocenter is important and full of challenges. We present...
3.
Chen T, Xiong Q, Xu H, Xiao L, Wang Z, Chang X, et al.
J Am Chem Soc
. 2024 Oct;
146(43):29928-29942.
PMID: 39418542
Chiral tetrahydro-β-carbolines, as one of the most intriguing subtypes of indole alkaloids, have emerged as the privileged units in plenty of natural products and biologically active molecules with an impressive...
4.
Yang H, Cheng X, Chang X, Wang Z, Dong X, Wang C
Chem Sci
. 2024 Jul;
15(26):10135-10145.
PMID: 38966363
The dual catalysis strategy is an efficient and powerful tool to fulfill the stereodivergent synthesis of stereoisomeric products from the same set of starting materials. Great attention has been given...
5.
Tian K, Chang X, Xiao L, Dong X, Wang C
Fundam Res
. 2024 Jun;
4(1):77-85.
PMID: 38933830
The development of stereodivergent synthetic methods to access all four stereoisomers of biologically important α-fluoro γ-butyrolactones containing vicinal stereocenters is of great importance and poses a formidable challenge owing to...
6.
Lu Y, Che C, Zhen G, Chang X, Dong X, Wang C
Chem Sci
. 2024 May;
15(17):6507-6514.
PMID: 38699278
An unprecedented intermolecular [4 + 2] cycloaddition of benzocyclobutylamines with α-substituted vinylketones, enabled by photoredox catalysis, has been developed. The current method enables facile access to highly functionalized cyclohexylamine derivatives...
7.
Wang W, Yi Z, Wang Z, Dong X, Wang C
Chem Commun (Camb)
. 2024 Apr;
60(38):5086-5089.
PMID: 38639097
Iridium-catalyzed dearomative allylation/acyl transfer rearrangement has been developed using easily available 2-pyridinyl benzoates and vinyl ethylene carbonate. This protocol enabled the expedient synthesis of a variety of chiral -substituted 2-pyridones...
8.
Liu G, Yang X, Gu P, Wang M, Zhang X, Dong X
J Am Chem Soc
. 2024 Mar;
146(11):7419-7430.
PMID: 38447583
The first earth-abundant transition metal Ni-catalyzed highly regio- and enantioselective semihydrogenation of racemic tetrasubstituted allenes via a kinetic resolution process as a challenging task was well established. This protocol furnishes...
9.
Han Z, Zhu B, Zang Y, Zhang C, Dong X, Huang H, et al.
Chem Sci
. 2024 Jan;
15(2):720-725.
PMID: 38179542
Demonstrated here is an asymmetric nucleophilic addition primary activation of -quinone methides (-QMs) based on a chiral phosphoric acid catalytic system. In sharp contrast to previous CPA-based bifunctional activation processes...
10.
Fu C, He L, Xu H, Zhang Z, Chang X, Dang Y, et al.
Nat Commun
. 2024 Jan;
15(1):127.
PMID: 38167331
Chiral functionalized piperidine and lactone heterocycles are widely spread in natural products and drug candidates with promising pharmacological properties. However, there remains no general asymmetric methodologies that enable rapid assemble...