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Zhaowei Sun

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Articles 51
Citations 609
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Recent Articles
1.
Wang Q, Sun Z, Guo J, Li H, Zhang J, Zhang B, et al.
Cancer Lett . 2025 Mar; :217596. PMID: 40081462
M2 macrophages play a critical role in the tumor microenvironment of invasive solid tumors. They are closely associated with perineural invasion (PNI) and are often linked to poor prognosis. In...
2.
Wang Q, Sun Z, Wang M, Feng C, Chen M, Li H, et al.
Genomics . 2025 Mar; :111028. PMID: 40064358
Cholangiocarcinoma is characterized by its high malignancy, frequent recurrence and insensitivity to conventional radiotherapy and chemotherapy. This resistance may be associated with the presence of cells in the G0/G1 arrest...
3.
Lu Y, Gao J, Hou Y, Yang H, Wang D, Zhang G, et al.
J Immunother Cancer . 2025 Jan; 13(1. PMID: 39773567
Background: Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of many malignant tumors. However, ICI-induced hyper-immune activation causes cardiotoxicity. Traditional treatments such as glucocorticoids and immunosuppressants have limited effectiveness and...
4.
Liu B, Dong K, Chen X, Dong H, Zhao Y, Wang X, et al.
Brain Sci . 2024 Nov; 14(11). PMID: 39595861
Background: Growing evidence suggests that glucose metabolism plays a crucial role in activated immune cells, significantly contributing to the occurrence and development of neuroinflammation and depression-like behaviors. Chronic stress has...
5.
Guo J, Wang M, Xue S, Wang Q, Wang M, Sun Z, et al.
Eur J Surg Oncol . 2024 Nov; 51(1):109361. PMID: 39547131
Objectives: The research aimed to create and verify a nomogram model that can predict the likelihood of cholangiocarcinoma with microvascular invasion (MVI). Methods: The clinical data of 476 patients with...
6.
Cui C, Du M, Zhao Y, Tang J, Liu M, Min G, et al.
ACS Appl Mater Interfaces . 2024 Sep; 16(40):53460-53473. PMID: 39303016
Tumor necrosis factor-α (TNF-α) plays a causal role in the pathogenesis of ulcerative colitis (UC), and anti-TNF-α siRNA shows great promise in UC therapy. However, delivering siRNA with site-targeted stability...
7.
Cui X, Guo J, Yuan P, Dai Y, Du P, Yu F, et al.
ACS Nano . 2024 Aug; 18(36):24622-24649. PMID: 39185722
Biobased therapy represents a promising strategy for myocardial repair. However, the limitations of using live cells, including the risk of immunogenicity of allogeneic cells and inconsistent therapeutic efficacy of autologous...
8.
Zhang L, Xie F, Wang X, Sun Z, Hu H, Wu Y, et al.
Biochem Pharmacol . 2024 Jul; 226:116410. PMID: 38969302
Elevated homocysteine (Hcy) levels are detrimental to neuronal cells and contribute to cognitive dysfunction in rats. Mitochondria plays a crucial role in cellular energy metabolism. Interestingly, the damaging effects of...
9.
Wu Y, Hu H, Liu W, Zhao Y, Xie F, Sun Z, et al.
Brain Sci . 2024 Apr; 14(4). PMID: 38671979
Lactate has emerged as a key player in regulating neural functions and cognitive processes. Beyond its function as an energy substrate and signal molecule, recent research has revealed lactate to...
10.
Wang X, Wu Y, Tian Y, Hu H, Zhao Y, Xue B, et al.
Cell Biosci . 2024 Apr; 14(1):48. PMID: 38627830
Background: Stress is a recognized risk factor for cognitive decline, which triggers neuroinflammation involving microglial activation. However, the specific mechanism for microglial activation under stress and affects learning and memory...