Zhaochun Xu
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Explore the profile of Zhaochun Xu including associated specialties, affiliations and a list of published articles.
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33
Citations
382
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Recent Articles
1.
Luo Z, Wang Q, Xia Y, Zhu X, Yang S, Xu Z, et al.
Front Genet
. 2025 Jan;
15():1464976.
PMID: 39845187
Cysteine S-carboxyethylation, a novel post-translational modification (PTM), plays a critical role in the pathogenesis of autoimmune diseases, particularly ankylosing spondylitis. Accurate identification of S-carboxyethylation modification sites is essential for elucidating...
2.
Luo Z, Yu L, Xu Z, Liu K, Gu L
Biology (Basel)
. 2024 Oct;
13(10).
PMID: 39452086
N6-methyladenosine (mA) plays a crucial regulatory role in the control of cellular functions and gene expression. Recent advances in sequencing techniques for transcriptome-wide mA mapping have accelerated the accumulation of...
3.
Ding Q, Yang W, Xue G, Liu H, Cai Y, Que J, et al.
Genome Biol
. 2024 Sep;
25(1):241.
PMID: 39252099
Advances in single-cell transcriptomics provide an unprecedented opportunity to explore complex biological processes. However, computational methods for analyzing single-cell transcriptomics still have room for improvement especially in dimension reduction, cell...
4.
Yang W, Wang P, Xu S, Wang T, Luo M, Cai Y, et al.
Nat Commun
. 2024 Aug;
15(1):7101.
PMID: 39155292
The inference of cell-cell communication (CCC) is crucial for a better understanding of complex cellular dynamics and regulatory mechanisms in biological systems. However, accurately inferring spatial CCCs at single-cell resolution...
5.
Cai Y, Luo M, Yang W, Xu C, Wang P, Xue G, et al.
Cancer Res
. 2024 Mar;
84(11):1915-1928.
PMID: 38536129
Significance: Development of a deep learning-based method for multicancer detection using the TCR repertoire in the peripheral blood establishes the potential of evaluating circulating immune signals for noninvasive early cancer...
6.
Xiao L, Sun H, Cheng R, Yang R, Jin X, Xu Z, et al.
Mol Ther Nucleic Acids
. 2024 Feb;
35(1):102129.
PMID: 38370981
Circulating tumor cells (CTCs) that undergo epithelial-to-mesenchymal transition (EMT) can provide valuable information regarding metastasis and potential therapies. However, current studies on the EMT overlook alternative splicing. Here, we used...
7.
Yu L, Xu Z, Qiu W, Xiao X
Comput Biol Med
. 2023 Dec;
169:107812.
PMID: 38091725
Unexpected side effects may accompany the research stage and post-marketing of drugs. These accidents lead to drug development failure and even endanger patients' health. Thus, it is essential to recognize...
8.
Yang W, Wang P, Luo M, Cai Y, Xu C, Xue G, et al.
Bioinformatics
. 2023 Sep;
39(10).
PMID: 37740953
Motivation: Cell-cell interactions (CCIs) play critical roles in many biological processes such as cellular differentiation, tissue homeostasis, and immune response. With the rapid development of high throughput single-cell RNA sequencing...
9.
Yang Q, Xu Z, Zhou W, Wang P, Jiang Q, Juan L
Brief Bioinform
. 2023 May;
24(4).
PMID: 37225419
Single-cell RNA sequencing (scRNA-seq) detects whole transcriptome signals for large amounts of individual cells and is powerful for determining cell-to-cell differences and investigating the functional characteristics of various cell types....
10.
Jin X, Cai Y, Xue G, Que J, Cheng R, Yang Y, et al.
Mol Ther Nucleic Acids
. 2023 Apr;
32:189-202.
PMID: 37096165
Tumor-infiltrating T cells are essential players in tumor immunotherapy. Great progress has been achieved in the investigation of T cell heterogeneity. However, little is well known about the shared characteristics...