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Zhao Ming Liu

Explore the profile of Zhao Ming Liu including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 7
Citations 31
Followers 0
Related Specialties
Biology
Pharmacology
Cell Biology
Top 10 Co-Authors
Qi Ming Li
Jun Wei Hou
Ji Guo Su
Yu Qin Jin
Xue Feng Zhang
Shuai Shao
Jing Zhang
Yu Liang
Zi Bo Han
Li Fang Du
Published In
Cell Discov
J Virol
Science
Elife
NPJ Vaccines
Affiliations
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Recent Articles
1.
Mutating a flexible region of the RSV F protein can stabilize the prefusion conformation
Liang Y, Shao S, Li X, Zhao Z, Liu N, Liu Z, et al.
Science . 2024 Sep; 385(6716):1484-1491. PMID: 39325881
The respiratory syncytial virus (RSV) fusion (F) glycoprotein is highly immunogenic in its prefusion (pre-F) conformation. However, the protein is unstable, and its conformation must be stabilized for it to...
2.
Prediction of mutation-induced protein stability changes based on the geometric representations learned by a self-supervised method
Li S, Liu Z, Li J, Ma Y, Dong Z, Hou J, et al.
BMC Bioinformatics . 2024 Aug; 25(1):282. PMID: 39198740
Background: Thermostability is a fundamental property of proteins to maintain their biological functions. Predicting protein stability changes upon mutation is important for our understanding protein structure-function relationship, and is also...
3.
Design of hepadnavirus core protein-based chimeric virus-like particles carrying epitopes from respiratory syncytial virus
Shao S, Zhang X, Hou J, Yang S, Han Z, Wu H, et al.
NPJ Vaccines . 2024 Mar; 9(1):62. PMID: 38503757
Respiratory syncytial virus (RSV) is one of the most important pathogens causing respiratory tract infection in humans, especially in infants and the elderly. The identification and structural resolution of the...
4.
Chimeric virus-like particles of human norovirus constructed by structure-guided epitope grafting elicit cross-reactive immunity against both GI.1 and GII.4 genotypes
Hou Y, Jin Y, Zhang X, Tang F, Hou J, Liu Z, et al.
J Virol . 2023 Oct; 97(10):e0093823. PMID: 37792003
Human norovirus (HuNoV) is highly infectious and can result in severe illnesses in the elderly and children. So far, there is no effective antiviral drug to treat HuNoV infection, and...
5.
Safety and immunogenicity of a mosaic vaccine booster against Omicron and other SARS-CoV-2 variants: a randomized phase 2 trial
Al Kaabi N, Yang Y, Liang Y, Xu K, Zhang X, Kang Y, et al.
Signal Transduct Target Ther . 2023 Jan; 8(1):20. PMID: 36596779
An ongoing randomized, double-blind, controlled phase 2 trial was conducted to evaluate the safety and immunogenicity of a mosaic-type recombinant vaccine candidate, named NVSI-06-09, as a booster dose in subjects...
6.
A mosaic-type trimeric RBD-based COVID-19 vaccine candidate induces potent neutralization against Omicron and other SARS-CoV-2 variants
Zhang J, Han Z, Liang Y, Zhang X, Jin Y, Du L, et al.
Elife . 2022 Aug; 11. PMID: 36004719
Large-scale populations in the world have been vaccinated with COVID-19 vaccines, however, breakthrough infections of SARS-CoV-2 are still growing rapidly due to the emergence of immune-evasive variants, especially Omicron. It...
7.
Design of a mutation-integrated trimeric RBD with broad protection against SARS-CoV-2
Liang Y, Zhang J, Yuan R, Wang M, He P, Su J, et al.
Cell Discov . 2022 Feb; 8(1):17. PMID: 35169113
The continuous emergence of SARS-CoV-2 variants highlights the need of developing vaccines with broad protection. Here, according to the immune-escape capability and evolutionary convergence, the representative SARS-CoV-2 strains carrying the...