Zhangyan Guo
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Explore the profile of Zhangyan Guo including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
345
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0
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Recent Articles
1.
Wei Y, Wang P, Zhao J, Fan X, Jiang J, Mu X, et al.
Cell Death Dis
. 2025 Jan;
16(1):47.
PMID: 39865088
Glioblastoma (GBM) is the most common malignant primary brain cancer with poor prognosis due to the resistant to current treatments, including the first-line drug temozolomide (TMZ). Accordingly, it is urgent...
2.
Yi W, Wang W, Zhang H, Wang Y, Zhou Y, Guo Z, et al.
Int J Gen Med
. 2024 Jun;
17:2701-2709.
PMID: 38895048
Background: In Asia, Hanta virus (HTNV) results in severe hemorrhagic fever with renal syndrome (HFRS). The efficacy of sivelestat in treating children with HTNV-induced HFRS remains unclear. Methods: An ambispective...
3.
Wang M, Zhou Y, Wang Y, Du Y, Guo Z, Ma L, et al.
Front Pediatr
. 2023 May;
11:1168205.
PMID: 37215590
Background: Hemorrhagic fever with Renal Syndrome (HFRS) is an infectious disease caused by Hantavirus with fever, hemorrhage and acute kidney injury (AKI) as clinical characteristics. The research on the etiology...
4.
Guo Z, Zhang R, Yang A, Zheng G
Front Immunol
. 2023 Mar;
14:1121285.
PMID: 36960057
Finding effective treatments for cancer remains a challenge. Recent studies have found that the mechanisms of tumor evasion are becoming increasingly diverse, including abnormal expression of immune checkpoint molecules on...
5.
Wang Y, Wang M, Zhang H, Wang Y, Du Y, Guo Z, et al.
Transl Pediatr
. 2022 Nov;
11(10):1671-1681.
PMID: 36345446
Background: Sivelestat, a neutrophil elastase inhibitor, is a selective and targeted therapy for acute respiratory distress syndrome (ARDS) in adults; and it is also reported to apply to children with...
6.
Du Y, Zhang Z, Chen C, Xia H, Zhang H, Guo Z, et al.
Front Pediatr
. 2022 Jul;
10:894049.
PMID: 35874573
Objective: To report the clinical features of the first child with infective endocarditis (IE) caused by in mainland China and to raise awareness of the disease. Methods: The clinical data...
7.
Zheng G, Guo Z, Li W, Xi W, Zuo B, Zhang R, et al.
Signal Transduct Target Ther
. 2021 Jun;
6(1):236.
PMID: 34158475
Despite the successful use of the humanized monoclonal antibody trastuzumab (Herceptin) in the clinical treatment of human epidermal growth factor receptor 2 (HER2)-overexpressing breast cancer, the frequently occurring drug resistance...
8.
Wei F, Jing H, Wei M, Liu L, Wu J, Wang M, et al.
Aging (Albany NY)
. 2020 Dec;
12(24):26199-26220.
PMID: 33346749
Ring finger protein 2 (RNF2) is an important component of polycomb repressive complex 1. RNF2 is upregulated in many kinds of tumors, and elevated RNF2 expression is associated with a...
9.
Jiao D, Li Y, Yang F, Han D, Wu J, Shi S, et al.
Clin Transl Gastroenterol
. 2019 May;
10(5):1-7.
PMID: 31116141
Introduction: Prostate-specific membrane antigen (PSMA) was originally found to be specifically expressed in normal prostate, and its expression was upregulated in almost all stages of prostate cancer. In recent years,...
10.
Wei M, Jiao D, Han D, Wu J, Wei F, Zheng G, et al.
Oncotarget
. 2016 Dec;
8(3):5323-5338.
PMID: 28029659
RNF2, also known as RING1b or RING2, is identified as the catalytic subunit of polycomb repressive complex 1 (PRC1), which mediates the mono-ubiquitination of histone H2A. RNF2 has been proved...