An-Gang Yang
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Explore the profile of An-Gang Yang including associated specialties, affiliations and a list of published articles.
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Articles
135
Citations
2337
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Recent Articles
1.
Chimeric antigen receptor with novel intracellular modules improves antitumor performance of T cells
Wang P, Wang Y, Zhao X, Zheng R, Zhang Y, Meng R, et al.
Signal Transduct Target Ther
. 2025 Jan;
10(1):20.
PMID: 39809749
The excessive cytokine release and limited persistence represent major challenges for chimeric antigen receptor T (CAR-T) cell therapy in diverse tumors. Conventional CARs employ an intracellular domain (ICD) from the...
2.
Mu X, Wei Y, Fan X, Zhang R, Xi W, Zheng G, et al.
Cell Death Discov
. 2024 Oct;
10(1):422.
PMID: 39353886
Chemotherapeutic drugs, such as cisplatin (cis-dichlorodiamineplatinum [II], cDDP) and 5-fluorouracil (5Fu), are widely used in transarterial chemoembolization (TACE), which is a standard therapy for patients with hepatocellular carcinoma (HCC). Chemoresistance...
3.
Guo Z, Zhang R, Yang A, Zheng G
Front Immunol
. 2023 Mar;
14:1121285.
PMID: 36960057
Finding effective treatments for cancer remains a challenge. Recent studies have found that the mechanisms of tumor evasion are becoming increasingly diverse, including abnormal expression of immune checkpoint molecules on...
4.
Shi S, Han D, Zhang J, Li Y, Yang A, Zhang R
Int J Oncol
. 2023 Feb;
62(3).
PMID: 36734275
VIM‑AS1, a cancer‑specific long non‑coding RNA, has been recognized as a pivotal regulator in multiple types of cancer. However, the role of VIM‑AS1 in the proliferation and resistance to anti‑androgen...
5.
Liu S, Han D, Xu C, Yang F, Li Y, Zhang K, et al.
Mol Med
. 2022 Mar;
28(1):37.
PMID: 35317721
Background: Chronic liver injury induces pathological repair, resulting in fibrosis, during which hepatic stellate cells (HSCs) are activated and transform into myofibroblasts. CD248 is mainly expressed on myofibroblasts and was...
6.
Jiao J, Jiao D, Yang F, Zhang J, Li Y, Han D, et al.
Aging (Albany NY)
. 2022 Feb;
14(4):1879-1890.
PMID: 35202002
Objectives: The aim of this study was to explore the expression of Galectin-9 in hepatitis B virus (HBV)-associated hepatocellular carcinoma (HCC), evaluate its clinicopathological significance, and investigate whether Galecin-9 expression...
7.
Zheng G, Jia L, Yang A
Front Immunol
. 2022 Feb;
13:791975.
PMID: 35185887
Human leukocyte antigen (HLA)-G is a nonclassical MHC Class I molecule, which was initially reported as a mediator of immune tolerance when expressed in extravillous trophoblast cells at the maternal-fetal...
8.
Peng S, Ma S, Yang F, Xu C, Li H, Lu S, et al.
Sci Rep
. 2022 Feb;
12(1):2219.
PMID: 35140317
Bladder cancer (BLCA) is the most common malignancy whose early diagnosis can ensure a better prognosis. However, the predictive accuracy of commonly used predictors, including patients' general condition, histological grade,...
9.
Jiang M, Liu F, Yang A, Wang W, Zhang R
Mol Ther Oncolytics
. 2022 Jan;
24:127-138.
PMID: 35024439
Head and neck cancers are a heterogeneous collection of malignancies of the upper aerodigestive tract, salivary glands, and thyroid. However, the molecular mechanisms underlying the carcinogenesis of head and neck...
10.
Antibody-drug conjugates targeting CD248 myofibroblasts effectively alleviate renal fibrosis in mice
Xu C, Liu S, Yang F, Zhang K, Li Y, Zhao X, et al.
FASEB J
. 2021 Dec;
36(2):e22102.
PMID: 34972243
Myofibroblasts, or activated fibroblasts, play a critical role in the process of renal fibrosis. Targeting myofibroblasts to inhibit their activation or induce specific cell death has been considered to be...