Zhangji Dong
Overview
Explore the profile of Zhangji Dong including associated specialties, affiliations and a list of published articles.
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36
Citations
258
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Recent Articles
1.
Guan T, Zhang W, Li M, Wang Q, Guo L, Guo B, et al.
Cell Signal
. 2025 Jan;
127:111615.
PMID: 39855534
Angiogenesis, a meticulously regulated process essential for both normal development and pathological conditions, necessitates a comprehensive understanding of the endothelial mechanisms governing its progression. Leveraging the zebrafish model and NgAgo...
2.
Dong Z, Zhuo R, Wang Q, Sun Y, Zhou Z, Wu R, et al.
Int Immunopharmacol
. 2024 Dec;
146():113874.
PMID: 39709909
The role of immune cells is crucial in nerve regeneration following spinal cord injury. Kif15, a member of the kinesin family, has been shown to enhance macrophage phagocytosis. This study...
3.
Sun Y, Ramakrishnan S, Lai X, Wu R, Dong Z, Qiang L, et al.
Biochim Biophys Acta Mol Cell Res
. 2024 Dec;
1872(2):119890.
PMID: 39681249
Microtubule-severing enzymes such as spastin, katanin, and fidgetin, characterized by their AAA ATPase domains, are pivotal in modulating microtubule dynamics and behavior across various cellular processes. While spastin and katanin...
4.
Ramakrishnan S, Mohan N, Dong Z, Liu M, Qiang L
Mov Disord
. 2024 Nov;
PMID: 39614608
Spastic Paraplegia 4 (SPG4) is a debilitating neurodegenerative disorder characterized by progressive muscle weakness and spasticity in the lower limbs, often leading to gait impairment. Central to SPG4 pathology is...
5.
Wu R, Ramakrishnan S, Lin H, Dong Z, Liu M, Qiang L
Metab Brain Dis
. 2024 Nov;
40(1):17.
PMID: 39560839
Corticospinal motor neurons (CSMNs), also named upper motor neurons, are the giant pyramidal neurons called Betz cells. In mammals, the majority of CSMNs reside within layer V of the primary...
6.
Dong Z, Wang Q, Yan Y, Qiang L, Liu M
Biochim Biophys Acta Mol Cell Res
. 2024 Oct;
1872(1):119870.
PMID: 39481482
The Fidgetin (FIGN) family, which comprises FIGN, Fidgetin-like 1 (FIGNL1), and Fidgetin-like 2 (FIGNL2), is a vital group of microtubule-severing proteins. These proteins feature a conserved AAA+ domain essential for...
7.
Wu R, Sun Y, Zhou Z, Dong Z, Liu Y, Liu M, et al.
Eur J Neurosci
. 2024 Apr;
59(12):3389-3402.
PMID: 38663879
Neurons are post-mitotic cells, with microtubules playing crucial roles in axonal transport and growth. Kinesin family member 2c (KIF2C), a member of the Kinesin-13 family, possesses the ability to depolymerize...
8.
Zhou Z, Wang P, Wang Q, Dong Z, Chen X, Zhuo R, et al.
Dev Biol
. 2023 Sep;
504:49-57.
PMID: 37741309
SAM and SH3 domain-containing 1 (SASH1), a member of the SLy protein family, is a tumor suppressor gene that has been studied for its association with various cancers. SASH1 is...
9.
Wu R, Lin H, Zhang W, Sun Y, Qian X, Lin G, et al.
J Biol Chem
. 2023 Aug;
299(9):105153.
PMID: 37567476
Astrocyte activation and proliferation contribute to glial scar formation during spinal cord injury (SCI), which limits nerve regeneration. The long noncoding RNAs (lncRNAs) are involved in astrocyte proliferation and act...
10.
Ma C, Wang J, Tu Q, Bo W, Hu Z, Zhuo R, et al.
Neural Regen Res
. 2023 Jul;
18(12):2727-2732.
PMID: 37449637
Fidgetin, a microtubule-severing enzyme, regulates neurite outgrowth, axonal regeneration, and cell migration by trimming off the labile domain of microtubule polymers. Because maintenance of the microtubule labile domain is essential...