Zhang-Zhi Hu
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Explore the profile of Zhang-Zhi Hu including associated specialties, affiliations and a list of published articles.
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21
Citations
564
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Recent Articles
1.
Hu Z, Kagan B, Ariazi E, Rosenthal D, Zhang L, Li J, et al.
PLoS One
. 2011 Jul;
6(6):e20410.
PMID: 21738574
Background: Estrogen is a known growth promoter for estrogen receptor (ER)-positive breast cancer cells. Paradoxically, in breast cancer cells that have been chronically deprived of estrogen stimulation, re-introduction of the...
2.
Wang J, Torii M, Liu H, Hart G, Hu Z
BMC Bioinformatics
. 2011 Apr;
12:91.
PMID: 21466708
Background: Protein O-GlcNAcylation (or O-GlcNAc-ylation) is an O-linked glycosylation involving the transfer of β-N-acetylglucosamine to the hydroxyl group of serine or threonine residues of proteins. Growing evidences suggest that protein...
3.
Hu Z, Huang H, Wu C, Jung M, Dritschilo A, Riegel A, et al.
Methods Mol Biol
. 2011 Mar;
719:547-71.
PMID: 21370102
Genomic, proteomic, and other omic-based approaches are now broadly used in biomedical research to facilitate the understanding of disease mechanisms and identification of molecular targets and biomarkers for therapeutic and...
4.
Torii M, Liu H, Hu Z
AMIA Annu Symp Proc
. 2010 Mar;
2009:640-4.
PMID: 20351933
Glycosylation is a common and complex protein post-translational modification (PTM). In particular, mucin-type O-linked glycosylation is abundant and plays important biological functions. The number of determined glycosylation sites is still...
5.
Integrated Bioinformatics for Radiation-Induced Pathway Analysis from Proteomics and Microarray Data
Hu Z, Huang H, Cheema A, Jung M, Dritschilo A, Wu C
J Proteomics Bioinform
. 2008 Dec;
1(2):47-60.
PMID: 19088860
Functional analysis and interpretation of large-scale proteomics and gene expression data require effective use of bioinformatics tools and public knowledge resources coupled with expert-guided examination. An integrated bioinformatics approach was...
6.
Torii M, Hu Z, Song M, Wu C, Liu H
BMC Bioinformatics
. 2007 Dec;
8 Suppl 9:S5.
PMID: 18047706
Motivation: With more and more research dedicated to literature mining in the biomedical domain, more and more systems are available for people to choose from when building literature mining applications....
7.
Huang H, Hu Z, Arighi C, Wu C
Front Biosci
. 2007 Jun;
12:5071-88.
PMID: 17569631
In the post-genome era, researchers are systematically tackling gene functions and complex regulatory processes by studying organisms on a global scale; however, a major challenge lies in the voluminous, complex,...
8.
Mazumder R, Hu Z, Vinayaka C, Sagripanti J, Frost S, Kosakovsky Pond S, et al.
Virus Genes
. 2007 May;
35(2):175-86.
PMID: 17508277
We have identified 72 completely conserved amino acid residues in the E protein of major groups of the Flavivirus genus by computational analyses. In the dengue species we have identified...
9.
Hu Z, Valencia J, Huang H, Chi A, Shabanowitz J, Hearing V, et al.
Int J Mass Spectrom
. 2007 Mar;
259(1-3):147-160.
PMID: 17375895
Complete and accurate profiling of cellular organelle proteomes, while challenging, is important for the understanding of detailed cellular processes at the organelle level. Mass spectrometry technologies coupled with bioinformatics analysis...
10.
Chi A, Valencia J, Hu Z, Watabe H, Yamaguchi H, Mangini N, et al.
J Proteome Res
. 2006 Nov;
5(11):3135-44.
PMID: 17081065
Melanin, which is responsible for virtually all visible skin, hair, and eye pigmentation in humans, is synthesized, deposited, and distributed in subcellular organelles termed melanosomes. A comprehensive determination of the...