Julio C Valencia
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Explore the profile of Julio C Valencia including associated specialties, affiliations and a list of published articles.
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47
Citations
1231
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Recent Articles
1.
Bafor E, Erwin-Cohen R, Martin T, Baker C, Kimmel A, Duverger O, et al.
Front Immunol
. 2024 May;
15:1368572.
PMID: 38698852
Introduction: Interferon-gamma (IFN-γ) is pivotal in orchestrating immune responses during healthy pregnancy. However, its dysregulation, often due to autoimmunity, infections, or chronic inflammatory conditions, is implicated in adverse reproductive outcomes...
2.
Bafor E, Martin T, Carrell J, Karwan M, Kimmel A, Omogiade U, et al.
STAR Protoc
. 2023 Nov;
4(4):102710.
PMID: 37963022
Here, we present a validated workflow to isolate sufficient viable single ovary cells from a single mouse without the need to pool from several mice. We provide steps essential for...
3.
Fenimore J, Springer D, Romero M, Edmondson E, McVicar D, Yanpallewar S, et al.
J Pathol
. 2023 May;
260(3):276-288.
PMID: 37185821
The effect of cytokines on non-traditional immunological targets under conditions of chronic inflammation is an ongoing subject of study. Fatigue is a symptom often associated with autoimmune diseases. Chronic inflammatory...
4.
Bafor E, Valencia J, Young H
Front Immunol
. 2022 Jul;
13:886645.
PMID: 35844500
Immune regulation of female reproductive function plays a crucial role in fertility, as alterations in the relationship between immune and reproductive processes result in autoimmune subfertility or infertility. The breakdown...
5.
Valencia J, Erwin-Cohen R, Clavijo P, Allen C, Sanford M, Day C, et al.
Cancer Res
. 2021 Oct;
81(23):5977-5990.
PMID: 34642183
The relationship between cancer and autoimmunity is complex. However, the incidence of solid tumors such as melanoma has increased significantly among patients with previous or newly diagnosed systemic autoimmune disease...
6.
Valencia J, Egbukichi N, Erwin-Cohen R
J Interferon Cytokine Res
. 2018 Dec;
39(1):72-84.
PMID: 30562133
Today, improvements in diagnostic and therapeutic options allow patients with autoimmune diseases (ADs) to live longer and have more active lives compared with patients receiving conventional anti-inflammatory therapy just two...
7.
Bae H, Hodge D, Yang G, Leung P, Chodisetti S, Valencia J, et al.
Hepatology
. 2017 Sep;
67(4):1408-1419.
PMID: 28921595
Conclusion: Our data implicate type I IFN signaling as a necessary component of the sex bias of this murine model of autoimmune cholangitis. Importantly these data suggest that drugs that...
8.
Green D, Young H, Valencia J
J Biol Chem
. 2017 Jun;
292(34):13925-13933.
PMID: 28652404
Interferon γ (IFNγ) is a pleiotropic protein secreted by immune cells. IFNγ signals through the IFNγ receptor, a protein complex that mediates downstream signaling events. Studies into IFNγ signaling have...
9.
Bae H, Leung P, Tsuneyama K, Valencia J, Hodge D, Kim S, et al.
Hepatology
. 2016 May;
64(4):1189-201.
PMID: 27178326
Unlabelled: In most autoimmune diseases the serologic hallmarks of disease precede clinical pathology by years. Therefore, the use of animal models in defining early disease events becomes critical. We took...
10.
Identification of Genes Expressed in Hyperpigmented Skin Using Meta-Analysis of Microarray Data Sets
Yin L, Coelho S, Valencia J, Ebsen D, Mahns A, Smuda C, et al.
J Invest Dermatol
. 2015 May;
135(10):2455-2463.
PMID: 25950827
More than 375 genes have been identified that are involved in regulating skin pigmentation and these act during development, survival, differentiation, and/or responses of melanocytes to the environment. Many of...