Zeyun Lu
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Explore the profile of Zeyun Lu including associated specialties, affiliations and a list of published articles.
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12
Citations
105
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Recent Articles
1.
Wang J, Zhang Z, Lu Z, Mancuso N, Gazal S
Am J Hum Genet
. 2024 Aug;
111(10):2117-2128.
PMID: 39191255
Multi-ancestry genome-wide association studies (GWASs) have highlighted the existence of variants with ancestry-specific effect sizes. Understanding where and why these ancestry-specific effects occur is fundamental to understanding the genetic basis...
2.
Kim A, Zhang Z, Legros C, Lu Z, de Smith A, Moore J, et al.
medRxiv
. 2024 May;
PMID: 38798383
The heritability of human diseases is extremely enriched in candidate regulatory elements (cRE) from disease-relevant cell types. Critical next steps are to infer which and how many cell types are...
3.
Lu Z, Wang X, Carr M, Kim A, Gazal S, Mohammadi P, et al.
medRxiv
. 2024 May;
PMID: 38699369
Multi-ancestry statistical fine-mapping of -molecular quantitative trait loci (-molQTL) aims to improve the precision of distinguishing causal -molQTLs from tagging variants. However, existing approaches fail to reflect shared genetic architectures....
4.
Wang Q, Li B, Qiu Z, Lu Z, Hang Z, Wu F, et al.
Plants (Basel)
. 2024 Feb;
13(3).
PMID: 38337970
Tree peony ( Andr.) is a traditional Chinese flower with significant ornamental and medicinal value. Its growth and development process is regulated by some internal and external factors, and the...
5.
Wang A, Shen J, Rodriguez A, Saunders E, Chen F, Janivara R, et al.
Nat Genet
. 2023 Nov;
55(12):2065-2074.
PMID: 37945903
The transferability and clinical value of genetic risk scores (GRSs) across populations remain limited due to an imbalance in genetic studies across ancestrally diverse populations. Here we conducted a multi-ancestry...
6.
Jung J, Lu Z, de Smith A, Mancuso N
Hum Mol Genet
. 2023 Oct;
33(2):170-181.
PMID: 37824084
Stroke, characterized by sudden neurological deficits, is the second leading cause of death worldwide. Although genome-wide association studies (GWAS) have successfully identified many genomic regions associated with ischemic stroke (IS),...
7.
Wang X, Lu Z, Bhattacharya A, Pasaniuc B, Mancuso N
Bioinformatics
. 2023 Apr;
39(5).
PMID: 37099718
Summary: Genome-wide association studies (GWASs) have identified numerous genetic variants associated with complex disease risk; however, most of these associations are non-coding, complicating identifying their proximal target gene. Transcriptome-wide association...
8.
Jung J, Lu Z, de Smith A, Mancuso N
medRxiv
. 2023 Apr;
PMID: 37034585
Stroke, characterized by sudden neurological deficits, is the second leading cause of death worldwide. Although genome-wide association studies (GWAS) have successfully identified many genomic regions associated with ischemic stroke (IS),...
9.
Zhu X, Zhu H, Ji W, Hong E, Lu Z, Li B, et al.
Front Plant Sci
. 2022 Nov;
13:1046881.
PMID: 36407591
The efficient induction of peony embryogenic callus is of great significance to the improvement and establishment of its regeneration technology system. In this study, the embryos of 'Fengdanbai' at different...
10.
Lu Z, Gopalan S, Yuan D, Conti D, Pasaniuc B, Gusev A, et al.
Am J Hum Genet
. 2022 Aug;
109(8):1388-1404.
PMID: 35931050
Transcriptome-wide association studies (TWASs) are a powerful approach to identify genes whose expression is associated with complex disease risk. However, non-causal genes can exhibit association signals due to confounding by...