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Ze-Yu Shuang

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Articles 7
Citations 207
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Recent Articles
1.
Sun H, Wu W, Chen H, Xu Y, Yang Y, Chen J, et al.
Front Immunol . 2021 Feb; 11:616367. PMID: 33603745
Solid tumors are often challenged by hypoxic and nutrient-deprived tumor microenvironments (TME) as tumors progress, due to limited perfusion and rapid nutrient consumption. While cancer cells can demonstrate the ability...
2.
Wu W, Sun H, Chen J, OuYang H, Yu X, Chen H, et al.
Cancer Immunol Res . 2019 Aug; 7(10):1605-1618. PMID: 31387898
Tumor-associated myeloid cells are one of the prominent components of solid tumors, serving as major immune regulators for the tumor microenvironment (TME) and an obstacle for immune-checkpoint blocking (ICB) therapy....
3.
Xu L, Wang J, Kim Y, Shuang Z, Zhang Y, Lao X, et al.
Oncoimmunology . 2016 May; 5(3):e1083671. PMID: 27141337
Background & Aims: There is no generally accepted adjuvant therapy for hepatocellular carcinoma (HCC) after curative resection. Autologous cytokine-induced killer (CIK) cells therapy has been reported to improve outcomes of...
4.
Chen J, Lao X, Lin X, Xu L, Cui B, Wang J, et al.
Medicine (Baltimore) . 2016 Feb; 95(5):e2665. PMID: 26844496
Cytokine-induced killer (CIK) cell therapy has recently been used as an adjuvant setting following resection of hepatocellular carcinoma (HCC), while its benefit remains unclear. This study aimed to evaluate the...
5.
Zhang M, Li S, Huang G, Lin G, Shuang Z, Lao X, et al.
BMC Cancer . 2015 Apr; 15:64. PMID: 25880914
Background: The clinical significance of microRNAs (miRNAs) in intrahepatic cholangiocarcinoma (ICC) is unclear. The objective of this study is to examine the miRNA expression profiles and identify a miRNA signature...
6.
Shuang Z, Wu W, Xu J, Lin G, Liu Y, Lao X, et al.
Cancer Lett . 2014 Sep; 354(2):320-8. PMID: 25194504
Epithelial-mesenchymal transition (EMT) is a major factor that facilitates the invasiveness and metastasis of cancer. Recent studies have demonstrated that EMT plays a key role in generating cancer stem cells...
7.
Zhang P, Wang X, Zhao W, Qi B, Yang Q, Wan H, et al.
J Biol Chem . 2014 Jul; 289(35):24724-35. PMID: 25049231
MicroRNAs (miRNAs) have been shown to play important roles in carcinogenesis. However, their underlying mechanisms of action in hepatocellular carcinoma (HCC) are poorly understood. Recent evidence suggests that epigenetic silencing...