Ze-qiang Ma
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Explore the profile of Ze-qiang Ma including associated specialties, affiliations and a list of published articles.
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14
Citations
476
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Recent Articles
1.
Liang K, Sun Y, Li W, Zhang X, Li C, Yang W, et al.
Diabetes Technol Ther
. 2014 Jul;
16(12):853-7.
PMID: 25014878
Background: Europeans and Americans are gradually accepting the hemoglobin A1c (HbA1c) threshold of 6.5% for diagnosing diabetes proposed by the American Diabetes Association, but the cutoff of HbA1c for the...
2.
Ma Z, Polzin K, Dasari S, Chambers M, Schilling B, Gibson B, et al.
Anal Chem
. 2012 Jun;
84(14):5845-50.
PMID: 22697456
LC-MS/MS-based proteomics studies rely on stable analytical system performance that can be evaluated by objective criteria. The National Institute of Standards and Technology (NIST) introduced the MSQC software to compute...
3.
Chen Y, Dasari S, Ma Z, Vega-Montoto L, Li M, Tabb D
Anal Bioanal Chem
. 2012 May;
404(4):1115-25.
PMID: 22552787
Spectral counting has become a widely used approach for measuring and comparing protein abundance in label-free shotgun proteomics. However, when analyzing complex samples, the ambiguity of matching between peptides and...
4.
Holman J, Ma Z, Tabb D
Curr Protoc Bioinformatics
. 2012 Mar;
Chapter 13:Unit13.17.
PMID: 22389012
The identification of peptides and proteins by LC-MS/MS requires the use of bioinformatics. Tools developed in the Tabb Laboratory contribute significant flexibility and discrimination to this process. The Bumbershoot tools...
5.
Ma Z, Tabb D, Burden J, Chambers M, Cox M, Cantrell M, et al.
Bioinformatics
. 2011 Oct;
27(22):3214-5.
PMID: 21965817
The large amount of data produced by proteomics experiments requires effective bioinformatics tools for the integration of data management and data analysis. Here we introduce a suite of tools developed...
6.
Ma Z, Chambers M, Ham A, Cheek K, Whitwell C, Aerni H, et al.
J Proteome Res
. 2011 Apr;
10(7):2896-904.
PMID: 21520941
In shotgun proteomics, protein identification by tandem mass spectrometry relies on bioinformatics tools. Despite recent improvements in identification algorithms, a significant number of high quality spectra remain unidentified for various...
7.
Li J, Su Z, Ma Z, Slebos R, Halvey P, Tabb D, et al.
Mol Cell Proteomics
. 2011 Mar;
10(5):M110.006536.
PMID: 21389108
Shotgun proteomics data analysis usually relies on database search. However, commonly used protein sequence databases do not contain information on protein variants and thus prevent variant peptides and proteins from...
8.
Ma Z, Dasari S, Chambers M, Litton M, Sobecki S, Zimmerman L, et al.
J Proteome Res
. 2009 Jun;
8(8):3872-81.
PMID: 19522537
Tandem mass spectrometry-based shotgun proteomics has become a widespread technology for analyzing complex protein mixtures. A number of database searching algorithms have been developed to assign peptide sequences to tandem...
9.
Tabb D, Ma Z, Martin D, Ham A, Chambers M
J Proteome Res
. 2008 Jul;
7(9):3838-46.
PMID: 18630943
In shotgun proteomics, tandem mass spectra of peptides are typically identified through database search algorithms such as Sequest. We have developed DirecTag, an open-source algorithm to infer partial sequence tags...
10.
Ma Z, Xie S, Huang Q, Nan F, Hurley T, Ye Q
BMC Struct Biol
. 2007 Dec;
7:84.
PMID: 18093325
Background: Methionine aminopeptidase is a potential target of future antibacterial and anticancer drugs. Structural analysis of complexes of the enzyme with its inhibitors provides valuable information for structure-based drug design...