Zachary R Fox
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Explore the profile of Zachary R Fox including associated specialties, affiliations and a list of published articles.
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12
Citations
104
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Recent Articles
1.
Saurabh A, Brown P, Iv J, Fox Z, Kruithoff R, Thompson C, et al.
Npj Imaging
. 2025 Feb;
3(1):5.
PMID: 39897617
Biological images captured by microscopes are characterized by heterogeneous signal-to-noise ratios (SNRs) due to spatially varying photon emission across the field of view convoluted with camera noise. State-of-the-art unsupervised structured...
2.
Saurabh A, Brown P, Bryan 4th J, Fox Z, Kruithoff R, Thompson C, et al.
bioRxiv
. 2023 Dec;
PMID: 38106139
Biological images captured by microscopes are characterized by heterogeneous signal-to-noise ratios (SNRs) due to spatially varying photon emission across the field of view convoluted with camera noise. State-of-the-art unsupervised structured...
3.
Fox Z, Batt G, Ruess J
Phys Biol
. 2023 Jun;
20(5).
PMID: 37343568
This study describes a method for controlling the production of protein in individual cells using stochastic models of gene expression. By combining modern microscopy platforms with optogenetic gene expression, experimentalists...
4.
Raymond W, Ghaffari S, Aguilera L, Ron E, Morisaki T, Fox Z, et al.
Front Cell Dev Biol
. 2023 Jun;
11:1151318.
PMID: 37325568
mRNA translation is the ubiquitous cellular process of reading messenger-RNA strands into functional proteins. Over the past decade, large strides in microscopy techniques have allowed observation of mRNA translation at...
5.
Raymond W, Ghaffari S, Aguilera L, Ron E, Morisaki T, Fox Z, et al.
bioRxiv
. 2023 Feb;
PMID: 36747627
mRNA translation is the ubiquitous cellular process of reading messenger-RNA strands into functional proteins. Over the past decade, large strides in microscopy techniques have allowed observation of mRNA translation at...
6.
Fox Z, Fletcher S, Fraisse A, Aditya C, Sosa-Carrillo S, Petit J, et al.
Nat Commun
. 2022 Apr;
13(1):2199.
PMID: 35459274
Microscopy image analysis has recently made enormous progress both in terms of accuracy and speed thanks to machine learning methods and improved computational resources. This greatly facilitates the online adaptation...
7.
Fox Z, Barkai E, Krapf D
Nat Commun
. 2021 Oct;
12(1):6162.
PMID: 34697310
Single-particle tracking offers detailed information about the motion of molecules in complex environments such as those encountered in live cells, but the interpretation of experimental data is challenging. One of...
8.
Jashnsaz H, Fox Z, Munsky B, Neuert G
STAR Protoc
. 2021 Jul;
2(3):100660.
PMID: 34286292
This protocol provides a step-by-step approach to perturb single cells with time-varying stimulation profiles, collect distinct signaling responses, and use these to infer a system of ordinary differential equations to...
9.
Jashnsaz H, Fox Z, Hughes J, Li G, Munsky B, Neuert G
iScience
. 2020 Oct;
23(10):101565.
PMID: 33083733
Computationally understanding the molecular mechanisms that give rise to cell signaling responses upon different environmental, chemical, and genetic perturbations is a long-standing challenge that requires models that fit and predict...
10.
Fox Z, Neuert G, Munsky B
Complexity
. 2020 Sep;
2020.
PMID: 32982137
Modern biological experiments are becoming increasingly complex, and designing these experiments to yield the greatest possible quantitative insight is an open challenge. Increasingly, computational models of complex stochastic biological systems...