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Zachary A Sexton

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Recent Articles
1.
Menon K, Khan M, Sexton Z, Richter J, Nguyen P, Malik S, et al.
Npj Imaging . 2024 May; 2(1):9. PMID: 38706558
Computational simulations of coronary artery blood flow, using anatomical models based on clinical imaging, are an emerging non-invasive tool for personalized treatment planning. However, current simulations contend with two related...
2.
Brown A, Sexton Z, Hu Z, Yang W, Marsden A
Curr Top Dev Biol . 2024 Mar; 156:19-50. PMID: 38556423
The cardiovascular development in vertebrates evolves in response to genetic and mechanical cues. The dynamic interplay among mechanics, cell biology, and anatomy continually shapes the hydraulic networks, characterized by complex,...
3.
Weiss A, Panduro A, Schwarz E, Sexton Z, Lan I, Geisbush T, et al.
Front Physiol . 2024 Jan; 14:1300754. PMID: 38162830
Initiation and progression of cerebral aneurysms is known to be driven by complex interactions between biological and hemodynamic factors, but the hemodynamic mechanism which drives aneurysm growth is unclear. We...
4.
Menon K, Khan M, Sexton Z, Richter J, Nieman K, Marsden A
medRxiv . 2023 Aug; PMID: 37645850
Computational simulations of coronary artery blood flow, using anatomical models based on clinical imaging, are an emerging non-invasive tool for personalized treatment planning. However, current simulations contend with two related...
5.
Sexton Z, Hudson A, Herrmann J, Shiwarski D, Pham J, Szafron J, et al.
ArXiv . 2023 Aug; PMID: 37645046
Our ability to produce human-scale bio-manufactured organs is critically limited by the need for vascularization and perfusion. For tissues of variable size and shape, including arbitrarily complex geometries, designing and...
6.
Sexton Z, Perl J, Saul H, Trotsyuk A, Pietzsch J, Ruggles S, et al.
JAMA Health Forum . 2023 Aug; 4(8):e232260. PMID: 37540524
Importance: A wide variety of novel medical diagnostics and devices are determined safe and effective by the US Food and Drug Administration (FDA) each year, but to our knowledge the...
7.
Puluca N, Munsterer A, Prinzing A, Sexton Z, Lange R, Meyer-Saraei R, et al.
J Thorac Dis . 2020 Jul; 12(5):2443-2449. PMID: 32642150
Background: The aim of this study was to evaluate the hemodynamic effect of different suturing techniques for aortic valve replacement (AVR) . Whether or not the applied suturing technique impacts...