Yvonne K Mburu
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Explore the profile of Yvonne K Mburu including associated specialties, affiliations and a list of published articles.
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9
Citations
323
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Recent Articles
1.
Dangles O, Struelens Q, Ba M, Bonzi-Coulibaly Y, Charvis P, Emmanuel E, et al.
PLoS One
. 2022 Sep;
17(9):e0273083.
PMID: 36048882
The creation of global research partnerships is critical to produce shared knowledge for the implementation of the UN 2030 Agenda for Sustainable Development. Sustainability science promotes the coproduction of inter-...
2.
Cui Y, Franciszkiewicz K, Mburu Y, Mondot S, Le Bourhis L, Premel V, et al.
J Clin Invest
. 2015 Nov;
125(11):4171-85.
PMID: 26524590
Mucosal-associated invariant T cells (MAITs) have potent antimicrobial activity and are abundant in humans (5%-10% in blood). Despite strong evolutionary conservation of the invariant TCR-α chain and restricting molecule MR1,...
3.
Le Bourhis L, Mburu Y, Lantz O
Curr Opin Immunol
. 2013 Feb;
25(2):174-80.
PMID: 23422835
Mucosal associated invariant T (MAIT) cells are evolutionarily conserved T cells that are restricted by the non-classical MHC-1b molecule, MR1. MAIT cells are selected on hematopoietic cells, and exit the...
4.
Ferris L, Mburu Y, Mathers A, Fluharty E, Larregina A, Ferris R, et al.
J Invest Dermatol
. 2012 Sep;
133(2):460-8.
PMID: 22951718
Human beta-defensins (hBDs) are antimicrobial peptides that have an important role in innate immune responses at epithelial barriers such as the skin. However, the role that hBDs have in initiating...
5.
Mburu Y, Egloff A, Walker W, Wang L, Seethala R, Van Waes C, et al.
J Biol Chem
. 2011 Dec;
287(5):3581-90.
PMID: 22158872
The chemokine receptor CCR7 is a seven-transmembrane domain G-protein-coupled receptor that facilitates leukocyte migration to regional lymph nodes. Aberrant CCR7 expression in a number of human malignancies has been linked...
6.
Umemura N, Zhu J, Mburu Y, Forero A, Hsieh P, Muthuswamy R, et al.
Cancer Res
. 2011 Nov;
72(1):45-55.
PMID: 22058147
Ligands to several Toll-like receptors (TLR), which mediate innate immune responses and chronic inflammation have been used as adjuvants to immunotherapy to enhance their antitumor activity. In particular, double-stranded RNAs...
7.
Mburu Y, Abe K, Ferris L, Sarkar S, Ferris R
Carcinogenesis
. 2010 Nov;
32(2):168-74.
PMID: 21071608
The microenvironment of aerodigestive cancers contains tumor-promoting inflammatory signals often involved in innate immunity. The epithelial malignancy, squamous cell carcinoma of the head and neck (SCCHN), is characterized by secretion...
8.
Zhu J, Smith K, Hsieh P, Mburu Y, Chattopadhyay S, Sen G, et al.
J Immunol
. 2010 Apr;
184(10):5768-76.
PMID: 20382888
TLR3 is one of the major innate immune sensors of dsRNA. The signal transduction pathway activated by TLR3, upon binding to dsRNA, leads to the activation of two major transcription...
9.
Mburu Y, Wang J, Wood M, Walker W, Ferris R
Immunol Res
. 2007 Mar;
36(1-3):61-72.
PMID: 17337767
Chemokine receptor 7 (CCR7) mediates leukocyte adhesion and chemotaxis from peripheral sites of inflammation through lymphatic channels to secondary lymphoid organs. Aberrant CCR7 expression has been identified on certain tumor...