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Yvan Arsenijevic

Explore the profile of Yvan Arsenijevic including associated specialties, affiliations and a list of published articles. Areas
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Articles 76
Citations 1970
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Recent Articles
1.
Zabiegalov O, Berger A, Kamdar D, Adamou K, Tian C, Mbefo M, et al.
Cells . 2025 Feb; 14(4). PMID: 39996725
Three-dimensional retinal culture systems help to understand eye development and the pathology of disorders. There is a need for reporter stem cell lines to allow in vitro studies on retinal...
2.
Mazzeo L, Arsenijevic Y, Berger A
Adv Exp Med Biol . 2025 Feb; 1468:189-193. PMID: 39930194
Inherited retinal disorders (IRD) represent a heterogeneous group of retinal diseases, mainly leading to a progressive photoreceptor cell death, and for which almost no treatment exists. Despite the diversity in...
3.
Mercey O, Gadadhar S, Magiera M, Lebrun L, Kostic C, Moulin A, et al.
EMBO J . 2024 Nov; 43(24):6679-6704. PMID: 39528655
Microtubules, composed of conserved α/β-tubulin dimers, undergo complex post-translational modifications (PTMs) that fine-tune their properties and interactions with other proteins. Cilia exhibit several tubulin PTMs, such as polyglutamylation, polyglycylation, detyrosination,...
4.
Damodar K, Dubois G, Guillou L, Mamaeva D, Pequignot M, Erkilic N, et al.
Mol Ther . 2024 Oct; 32(12):4319-4336. PMID: 39385467
Inherited retinal diseases (IRDs) are characterized by progressive vision loss. There are over 270 causative IRD genes, and variants within the same gene can cause clinically distinct disorders. One example...
5.
Arsenijevic Y, Chang N, Mercey O, El Fersioui Y, Koskiniemi-Kuendig H, Joubert C, et al.
EMBO Mol Med . 2024 Mar; 16(4):805-822. PMID: 38504136
For 15 years, gene therapy has been viewed as a beacon of hope for inherited retinal diseases. Many preclinical investigations have centered around vectors with maximal gene expression capabilities, yet...
6.
Matsevich C, Gopalakrishnan P, Chang N, Obolensky A, Beryozkin A, Salameh M, et al.
Mol Ther . 2023 Aug; 31(10):2948-2961. PMID: 37580905
Photoreceptor cell degeneration and death is the major hallmark of a wide group of human blinding diseases including age-related macular degeneration and inherited retinal diseases such as retinitis pigmentosa. In...
7.
Arsenijevic Y, Berger A, Udry F, Kostic C
Pharmaceutics . 2022 Aug; 14(8). PMID: 36015231
This review offers the basics of lentiviral vector technologies, their advantages and pitfalls, and an overview of their use in the field of ophthalmology. First, the description of the global...
8.
Mercey O, Kostic C, Bertiaux E, Giroud A, Sadian Y, Gaboriau D, et al.
PLoS Biol . 2022 Jun; 20(6):e3001649. PMID: 35709082
Inherited retinal degeneration due to loss of photoreceptor cells is a leading cause of human blindness. These cells possess a photosensitive outer segment linked to the cell body through the...
9.
Canonica J, Zhao M, Favez T, Gelize E, Jonet L, Kowalczuk L, et al.
Int J Mol Sci . 2021 Sep; 22(17). PMID: 34502527
Glucocorticoids are amongst the most used drugs to treat retinal diseases of various origins. Yet, the transcriptional regulations induced by glucocorticoid receptor (GR) and mineralocorticoid receptor (MR) activation in retinal...
10.
Mbefo M, Berger A, Schouwey K, Gerard X, Kostic C, Beryozkin A, et al.
Int J Mol Sci . 2021 Sep; 22(17). PMID: 34502238
Inherited retinal dystrophies (IRD) are due to various gene mutations. Each mutated gene instigates a specific cell homeostasis disruption, leading to a modification in gene expression and retinal degeneration. We...