Yunhye Kim
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Explore the profile of Yunhye Kim including associated specialties, affiliations and a list of published articles.
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27
Citations
135
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Recent Articles
1.
Klouda T, Kim Y, Baek S, Bhaumik M, Li Y, Liu Y, et al.
EMBO J
. 2025 Jan;
44(4):1074-1106.
PMID: 39806101
Pericytes are essential for capillary stability and homeostasis, with impaired pericyte function linked to diseases like pulmonary arterial hypertension. Investigating pericyte biology has been challenging due to the lack of...
2.
Precision Medicine for Pulmonary Vascular Disease: The Future Is Now (2023 Grover Conference Series)
Forbes L, Bauer N, Bhadra A, Bogaard H, Choudhary G, Goss K, et al.
Pulm Circ
. 2025 Jan;
15(1):e70027.
PMID: 39749110
Pulmonary vascular disease is not a single condition; rather it can accompany a variety of pathologies that impact the pulmonary vasculature. Applying precision medicine strategies to better phenotype, diagnose, monitor,...
3.
Nguyen H, Jeong Y, Kim Y, Kamiya M, Kim Y, Athar H, et al.
Proc Natl Acad Sci U S A
. 2024 Dec;
121(50):e2401899121.
PMID: 39636853
Fibrosis drives end-organ damage in many diseases. However, clinical trials targeting individual upstream activators of fibroblasts, such as TGFβ, have largely failed. Here, we target the leukemia inhibitory factor receptor...
4.
Lee U, Zhang Y, Zhu Y, Luo A, Gong L, Tremmel D, et al.
Nat Commun
. 2024 Sep;
15(1):8392.
PMID: 39349465
Mural cells are central to vascular integrity and function. In this study, we demonstrate the innovative use of the transcription factor NKX3.1 to guide the differentiation of human induced pluripotent...
5.
Klouda T, Tsikis S, Hirsch T, Kim Y, Liu T, Friehs I, et al.
bioRxiv
. 2024 Sep;
PMID: 39314465
Patients with congenital heart disease (CHD) resulting in significant left-to-right shunting of blood are at risk for the development of pulmonary arterial hypertension (PAH). The underlying mechanism by which pulmonary...
6.
Nguyen L, Kim Y, Hur S, Byeon H, Ban M, Shim J, et al.
Biochem Biophys Res Commun
. 2024 Jul;
727:150291.
PMID: 38959734
Irradiation (IR)-induced xerostomia is the most common side effect of radiation therapy in patients with head and neck cancer (HNC). Xerostomia diagnosis is mainly based on the patient's medical history...
7.
Zhou Y, Tabib T, Huang M, Yuan K, Kim Y, Morse C, et al.
Arterioscler Thromb Vasc Biol
. 2024 Jun;
44(8):e210-e225.
PMID: 38841857
Background: Pulmonary hypertension (PH) is a common complication of systemic sclerosis (SSc) and a leading cause of mortality among patients with this disease. PH can also occur as an idiopathic...
8.
Nguyen H, Jeong Y, Kim Y, Kim Y, Athar H, Castaldi P, et al.
bioRxiv
. 2024 Jun;
PMID: 38826450
Significance Statement: Fibroblasts have a central role in the pathogenesis of fibrotic diseases. However, due to in part to multiple profibrotic stimuli, targeting a single activator of fibroblasts, like TGFβ,...
9.
Kim H, Liu Y, Kim J, Kim Y, Klouda T, Fisch S, et al.
EMBO Rep
. 2024 Jan;
25(2):616-645.
PMID: 38243138
Vascular remodeling is the process of structural alteration and cell rearrangement of blood vessels in response to injury and is the cause of many of the world's most afflicted cardiovascular...
10.
Labib M, Wang Z, Kim Y, Lin S, Abdrabou A, Yousefi H, et al.
Nat Biomed Eng
. 2023 Nov;
8(3):263-277.
PMID: 38012306
The identification of genetic regulators of cell secretions is challenging because it requires the sorting of a large number of cells according to their secretion patterns. Here we report the...