Yun-Xing Wang
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Explore the profile of Yun-Xing Wang including associated specialties, affiliations and a list of published articles.
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90
Citations
1414
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Recent Articles
1.
Stagno J, Deme J, Dwivedi V, Lee Y, Lee H, Yu P, et al.
Nucleic Acids Res
. 2025 Mar;
53(5).
PMID: 40071935
Synthetic RNA devices are engineered to control gene expression and offer great potential in both biotechnology and clinical applications. Here, we present multidisciplinary structural and biochemical data for a tetracycline...
2.
Degenhardt M, Degenhardt H, Bhandari Y, Lee Y, Ding J, Yu P, et al.
Nature
. 2024 Dec;
637(8048):1234-1243.
PMID: 39695231
Much of the human genome is transcribed into RNAs, many of which contain structural elements that are important for their function. Such RNA molecules-including those that are structured and well-folded-are...
3.
Lee Y, Degenhardt M, Skeparnias I, Degenhardt H, Bhandari Y, Yu P, et al.
Nature
. 2024 Dec;
637(8048):1244-1251.
PMID: 39695229
RNA conformational diversity has fundamental biological roles, but direct visualization of its full conformational space in solution has not been possible using traditional biophysical techniques. Using solution atomic force microscopy,...
4.
Stagno J, Wang Y
Int J Mol Sci
. 2024 Oct;
25(19).
PMID: 39409011
Riboswitches are highly structured RNA regulators of gene expression. Although found in all three domains of life, they are particularly abundant and widespread in bacteria, including many human pathogens, thus...
5.
Caba C, Black M, Liu Y, DaDalt A, Mallare J, Fan L, et al.
J Biol Chem
. 2024 Aug;
300(10):107727.
PMID: 39214302
Ubiquitin-specific proteases (USPs) are a family of multi-domain deubiquitinases (DUBs) with variable architectures, some containing regulatory auxiliary domains. Among the USP family, all occurrences of intramolecular regulation presently known are...
6.
Skeparnias I, Bou-Nader C, Anastasakis D, Fan L, Wang Y, Hafner M, et al.
Nat Struct Mol Biol
. 2024 Jul;
31(11):1655-1668.
PMID: 38956168
The metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) long noncoding RNA (lncRNA) has key roles in regulating transcription, splicing, tumorigenesis, etc. Its maturation and stabilization require precise processing by RNase P,...
7.
Suddala K, Yoo J, Fan L, Zuo X, Wang Y, Chung H, et al.
Nat Commun
. 2023 Sep;
14(1):5438.
PMID: 37673863
T-box riboswitches are multi-domain noncoding RNAs that surveil individual amino acid availabilities in most Gram-positive bacteria. T-boxes directly bind specific tRNAs, query their aminoacylation status to detect starvation, and feedback...
8.
Ding J, Deme J, Stagno J, Yu P, Lea S, Wang Y
Nucleic Acids Res
. 2023 Aug;
51(18):9952-9960.
PMID: 37534568
RNA conformational heterogeneity often hampers its high-resolution structure determination, especially for large and flexible RNAs devoid of stabilizing proteins or ligands. The adenosylcobalamin riboswitch exhibits heterogeneous conformations under 1 mM...
9.
Il Ahn J, Zhang L, Ravishankar H, Fan L, Kirsch K, Zeng Y, et al.
Commun Biol
. 2023 Jul;
6(1):784.
PMID: 37500946
No abstract available.
10.
Il Ahn J, Zhang L, Ravishankar H, Fan L, Kirsch K, Zeng Y, et al.
Commun Biol
. 2023 Jul;
6(1):712.
PMID: 37433832
Proper organization of intracellular assemblies is fundamental for efficient promotion of biochemical processes and optimal assembly functionality. Although advances in imaging technologies have shed light on how the centrosome is...