Yuk Fai Lau
Overview
Explore the profile of Yuk Fai Lau including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
492
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Recent Articles
1.
Tang L, Lim J, Kuah L, Lau Y
Vaccine
. 2014 Aug;
32(42):5375-8.
PMID: 25130540
A prototype H7 influenza vaccine constructed based on the H7N7 outbreak in 2003 was tested for the protective efficacy against the novel H7N9 virus in a lethal murine challenge model....
2.
Lau Y, Lau Y, Lai K, Lau C
Singapore Med J
. 2013 Nov;
54(11):e230-2.
PMID: 24276111
A 23-year-old man presented with abdominal pain after suffering blunt trauma caused by a seatbelt injury. His low platelet count of 137 × 10(9)/L was initially attributed to trauma and...
3.
Win M, Chow A, Chen M, Lau Y, Ooi E, Leo Y
Ann Acad Med Singap
. 2010 Jul;
39(6):448-52.
PMID: 20625620
Introduction: Outbreaks of acute respiratory illness occur commonly in long-term care facilities (LTCF), due to the close proximity of residents. Most influenza outbreak reports have been from temperate countries. This...
4.
Chen J, Lau Y, Lamirande E, Paddock C, Bartlett J, Zaki S, et al.
J Virol
. 2009 Nov;
84(3):1289-301.
PMID: 19906920
We characterized the cellular immune response to severe acute respiratory syndrome coronavirus (SARS-CoV) infection in 12- to 14-month-old BALB/c mice, a model that mimics features of the human disease. Following...
5.
Lau Y, Deliyannis G, Zeng W, Mansell A, Jackson D, Brown L
Int Immunol
. 2006 Nov;
18(12):1801-13.
PMID: 17077175
Anti-viral CD8(+) T cell responses can be induced using synthetic lipopeptides and a range of different lipid moieties have been examined in a variety of model systems and in man...
6.
Chua B, Zeng W, Lau Y, Jackson D
Vaccine
. 2006 Oct;
25(1):92-101.
PMID: 17055123
We have previously shown that incorporating the lipid moiety dipalmitoyl-S-glyceryl cysteine (Pam2Cys) into peptide structures effectively adjuvants otherwise weak immunogens. In this study lipopeptides based on luteinising hormone releasing hormone...
7.
Deliyannis G, Kedzierska K, Lau Y, Zeng W, Turner S, Jackson D, et al.
Eur J Immunol
. 2006 Jan;
36(3):770-8.
PMID: 16435281
The longevity of the influenza virus-specific CD8+ T cell response following intranasal delivery of a synthetic lipopeptide was investigated and the characteristics and location of the cells associated with viral...
8.
Jackson D, Lau Y, Le T, Suhrbier A, Deliyannis G, Cheers C, et al.
Proc Natl Acad Sci U S A
. 2004 Oct;
101(43):15440-5.
PMID: 15489266
A simple generic peptide-based vaccine structure that targets Toll-like receptor 2-expressing dendritic cells and causes their activation is described. The vaccines are totally synthetic, serve as their own adjuvant, and...
9.
Zeng W, Ghosh S, Lau Y, Brown L, Jackson D
J Immunol
. 2002 Oct;
169(9):4905-12.
PMID: 12391202
In this study, we describe the synthesis of various lipopeptides based on the sequence of luteinizing hormone-releasing hormone (LHRH) and report on their abilities to induce Abs against this "self"...