Weiguang Zeng
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Explore the profile of Weiguang Zeng including associated specialties, affiliations and a list of published articles.
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67
Citations
1417
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Recent Articles
1.
Tarwadi , Pambudi S, Sriherwanto C, Sasangka A, Bowolaksono A, Wijayadikusumah A, et al.
Int J Pharm
. 2024 Jul;
662:124492.
PMID: 39038720
Purposes: The objective of this study is to develop a versatile gene carrier based on lipopeptides capable of delivering genetic material into target cells with minimal cytotoxicity. Methods: Two lipopeptide...
2.
Deliyannis G, Gherardin N, Wong C, Grimley S, Cooney J, Redmond S, et al.
EBioMedicine
. 2023 May;
92:104574.
PMID: 37148585
Background: The SARS-CoV-2 global pandemic has fuelled the generation of vaccines at an unprecedented pace and scale. However, many challenges remain, including: the emergence of vaccine-resistant mutant viruses, vaccine stability...
3.
Deliyannis G, Wong C, McQuilten H, Bachem A, Clarke M, Jia X, et al.
JCI Insight
. 2021 Feb;
6(5).
PMID: 33561017
The impact of respiratory virus infections on global health is felt not just during a pandemic, but endemic seasonal infections pose an equal and ongoing risk of severe disease. Moreover,...
4.
Proud P, Tsitoura D, Watson R, Chua B, Aram M, Bewley K, et al.
EBioMedicine
. 2020 Dec;
63:103153.
PMID: 33279857
Background: The novel human coronavirus SARS-CoV-2 is a major ongoing global threat with huge economic burden. Like all respiratory viruses, SARS-CoV-2 initiates infection in the upper respiratory tract (URT). Infected...
5.
Mangas K, Buultjens A, Porter J, Baines S, Marion E, Marsollier L, et al.
Infect Immun
. 2019 Dec;
88(3).
PMID: 31818964
The neglected tropical disease Buruli ulcer (BU) is an infection of subcutaneous tissue with There is no effective vaccine. Here, we assessed an experimental prime-boost vaccine in a low-dose murine...
6.
Zeng W, Horrocks K, Tan A, Wong C, Chua B, Jackson D
Vaccine
. 2019 Nov;
38(3):597-607.
PMID: 31740096
To facilitate the preparation of synthetic epitope-based self-adjuvanting vaccines capable of eliciting antibody responses in an out-bred population, we have developed two modular approaches. In the first, the Toll-like receptor...
7.
Omansen T, Marcsisin R, Chua B, Zeng W, Jackson D, Porter J, et al.
Am J Trop Med Hyg
. 2019 Oct;
101(6):1312-1321.
PMID: 31595865
Buruli ulcer (BU) is a neglected tropical disease caused by infection with . Unclear transmission, no available vaccine, and suboptimal treatment regimens hamper the control of this disease. Carefully designed...
8.
Wijayadikusumah A, Zeng W, McQuilten H, Wong C, Jackson D, Chua B
Mol Pharm
. 2019 Mar;
16(5):2037-2047.
PMID: 30924661
Targeted delivery of otherwise nonimmunogenic antigens to Toll-like receptors (TLRs) expressed on dendritic cells (DCs) has proven to be an effective means of improving immunogenicity. For this purpose, we have...
9.
Koutsakos M, Illing P, Nguyen T, Mifsud N, Crawford J, Rizzetto S, et al.
Nat Immunol
. 2019 Feb;
20(5):613-625.
PMID: 30778243
Influenza A, B and C viruses (IAV, IBV and ICV, respectively) circulate globally and infect humans, with IAV and IBV causing the most severe disease. CD8 T cells confer cross-protection...
10.
Ernest M, Hunja C, Arakura Y, Haraga Y, M Abkallo H, Zeng W, et al.
Int J Parasitol Drugs Drug Resist
. 2018 Nov;
8(3):451-458.
PMID: 30396012
Both vaccine and therapeutic approaches to malaria are based on conventional paradigms; whole organism or single antigen epitope-based vaccines administered with or without an adjuvant, and chemotherapeutics (anti-malaria drugs) that...