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You-Yun Zhou

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Articles 16
Citations 159
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Recent Articles
1.
Yu Z, Han X, Li P, Zhao Y, Zhang X, Sun X, et al.
J Am Chem Soc . 2025 Jan; 147(5):3931-3936. PMID: 39868749
While synthesizing circular polymers with telechelic polyolefin building blocks recently emerged as a promising strategy for addressing conventional polyethylenes' sustainability challenges, the lack of telechelic PP (PP) with sufficient difunctional...
2.
Zhou L, Li L, Zhang S, Kuang X, Zhou Y, Tang Y
J Am Chem Soc . 2024 Jul; 146(28):18823-18830. PMID: 38950377
The catalytic regio- and enantioselective hydrocarboxylation of alkenes with carbon dioxide is a straightforward strategy to construct enantioenriched α-chiral carboxylic acids but remains a big challenge. Herein we report the...
3.
Zhang S, Li L, Li D, Zhou Y, Tang Y
J Am Chem Soc . 2024 Jan; 146(5):2888-2894. PMID: 38277681
Catalytic asymmetric carboxylation of readily available alkenes with CO, an abundant and sustainable one-carbon building block, that gives access to value-added α-stereogenic carboxylic acids in an atom- and step-economic manner...
4.
Guo J, Ma H, Xiong W, Fan L, Zhou Y, Wong H, et al.
Chem Sci . 2022 Dec; 13(46):13914-13921. PMID: 36544735
Herein, we report an efficient kinetic resolution of alkyl allylic alcohols enabled by an iridium-catalyzed enantioselective alkynylation of alkyl allylic alcohols with potassium alkynyltrifluoroborates. A wide range of chiral 1,4-enynes...
5.
Guo J, Xiong W, Ma H, Fan L, Zhou Y, Wong H, et al.
Chem Sci . 2022 Jun; 13(16):4608-4615. PMID: 35656141
We report herein a novel approach involving optical resolution of (±)-1,16-dihydroxytetraphenylene (DHTP) by chiral gold(iii) complexation. This method features several key advantages, , recyclability of chiral resolution reagents, feasibility of...
6.
Farley C, Sasakura K, Zhou Y, Kanale V, Uyeda C
J Am Chem Soc . 2020 Feb; 142(10):4598-4603. PMID: 32083863
Polysubstituted cyclohexenes bearing 1,3 () substitution patterns are challenging to access using the Diels-Alder reaction (the - rule). Here, we report a cobalt-catalyzed reductive [5 + 1]-cycloaddition between a vinylcyclopropane...
7.
Zhou Y, Uyeda C
Science . 2019 Feb; 363(6429):857-862. PMID: 30792299
Cycloaddition reactions provide direct and convergent routes to cycloalkanes, making them valuable targets for the development of synthetic methods. Whereas six-membered rings are readily accessible from Diels-Alder reactions, cycloadditions that...
8.
Farley C, Zhou Y, Banka N, Uyeda C
J Am Chem Soc . 2018 Sep; 140(40):12710-12714. PMID: 30216053
Cyclic structures are highly represented in organic molecules, motivating a wealth of catalytic methods targeting their synthesis. Among the various ring-forming processes, cyclooligomerization reactions possess several attractive features but require...
9.
Pal S, Zhou Y, Uyeda C
J Am Chem Soc . 2017 Aug; 139(34):11686-11689. PMID: 28806870
Methylenecyclopropanes are important synthetic intermediates that possess strain energies exceeding those of saturated cyclopropanes by >10 kcal/mol. This report describes a catalytic reductive methylenecyclopropanation reaction of simple olefins, utilizing 1,1-dichloroalkenes...
10.
Behlen M, Zhou Y, Steiman T, Pal S, Hartline D, Zeller M, et al.
Dalton Trans . 2016 Dec; 46(17):5493-5497. PMID: 27996067
A family of low-valent Ni, Co, and Fe naphthyridine-diimine (NDI) complexes is presented. Ligand-based π* orbitals are sufficiently low-lying to fall within the metal 3d manifold, resulting in electronic structures...